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IL-11 Protein (Fc Tag)

IL11 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Catalog No. ABIN7092795
  • Target See all IL-11 (IL11) Proteins
    IL-11 (IL11) (Interleukin 11 (IL11))
    Protein Type
    Recombinant
    Origin
    • 17
    • 10
    • 2
    • 2
    Human
    Source
    • 12
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This IL-11 protein is labelled with Fc Tag.
    Purpose
    Recombinant Human IL11 with C-terminal human Fc tag
    Specificity
    IL11 (Pro22-Leu199) hFc (Glu99-Ala330)
    Characteristics
    Extracellular Domain Protein
    Purification
    affinity purification
    Purity
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product IL11 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute with deionized water
    Buffer
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Expiry Date
    12 months
  • Target
    IL-11 (IL11) (Interleukin 11 (IL11))
    Alternative Name
    IL11 (IL11 Products)
    Synonyms
    IL11 Protein, AGIF Protein, IL-11 Protein, Il-11 Protein, interleukin 11 Protein, IL11 Protein, Il11 Protein
    Background
    Synonymes: AGIF
    Description: The protein encoded by this gene is a member of the gp130 family of cytokines. These cytokines drive the assembly of multisubunit receptor complexes, all of which contain at least one molecule of the transmembrane signaling receptor IL6ST (gp130). This cytokine is shown to stimulate the T-cell-dependent development of immunoglobulin-producing B cells. It is also found to support the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2012]
    Molecular Weight
    predicted molecular mass of 45.3 kDa after removal of the signal peptide. The apparent molecular mass of IL11-hFc is 55-70 kDa due to glycosylation.
    UniProt
    P20809
    Pathways
    JAK-STAT Signaling, Negative Regulation of Hormone Secretion
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