SARS-CoV-2 Spike S1 Protein (BA.3 - Omicron) (His tag)
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- Target See all SARS-CoV-2 Spike S1 Proteins
- SARS-CoV-2 Spike S1
- Protein Type
- Recombinant
- Protein Characteristics
- BA.3 - Omicron
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Origin
- SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Omicron
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This SARS-CoV-2 Spike S1 protein is labelled with His tag.
- Purpose
- SARS-CoV-2 Spike S1, His Tag (BA.3/Omicron)
- Sequence
- Val 16 - Arg 685
- Specificity
- SARS-CoV-2 Spike S1 (BA.3/Omicron)
- Characteristics
- SARS-CoV-2 Spike S1, His Tag (BA.3/Omicron) (S1N-C52Hq) is expressed from human 293 cells (HEK293). It contains AA Val 16 - Arg 685 (Accession # QHD43416.1 (A67V,H69del,V70del,T95I,G142D,V143del,Y144del,Y145del,N211del,L212I,G339D,S371F,S373P,S375F,D405N,K417N,N440K,G446S,S477N,T478K,E484A,Q493R,Q498R,N501Y,Y505H,D614G,H655Y,N679K,P681H). The spike mutations are identified on the SARS-CoV-2 Omicron variant (Pango lineage: BA.3, GISAID clade: GRA, Nextstrain clade: 21M).
- Purity
- >90 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product SARS-CoV-2 Spike S1 Protein
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- Application Notes
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 76.5 kDa. The protein migrates as kDa under reducing (R) condition due to glycosylation.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Storage
- -20 °C
- Storage Comment
- -20°C
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- Target
- SARS-CoV-2 Spike S1
- Abstract
- SARS-CoV-2 Spike S1 Products
- Synonyms
- E2 Protein, Surface Glycoprotein Protein, S Protein
- Target Type
- Viral Protein
- Background
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Synonyms: Spike,S1 protein,Spike glycoprotein Subunit1,S glycoprotein Subunit1,Spike protein S1,
Description: It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. - Molecular Weight
- 76.5 kDa
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