EGFRviii Protein (APC,His tag)
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- Target See all EGFRviii (EGFRv3) products
- EGFRviii (EGFRv3) (EGFR vIII (EGFRv3))
- Protein Type
- Recombinant
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This EGFRviii protein is labelled with APC,His tag.
- Purpose
- APC-Labeled Human EGFRvIII Protein, His Tag (Site-specific conjugation)
- Sequence
- Leu 25 - Ser 378
- Characteristics
- APC-Labeled Human EGFRvIII, His Tag (EGI-HA2H8) is produced via conjugation of APC to Human EGFRvIII, His Tag with a new generation site-specific technology under optimal conditions with a proprietary technology. Human EGFRvIII, His Tag is expressed from human 293 cells (HEK293). It contains AA Leu 25 - Ser 378 (Accession # NP_001333870.1).
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EGFR vIII (EGFRv3) (AA 25-378) protein (His-Avi Tag,Biotin)
EGFRv3 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
EGFR vIII (EGFRv3) protein (His-Avi Tag)EGFRv3 Origin: Human Host: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
EGFR vIII (EGFRv3) (AA 25-378) protein (FITC,His-Avi Tag)EGFRv3 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
EGFR vIII (EGFRv3) (AA 25-378) protein (PE,His-Avi Tag)EGFRv3 Origin: Human Host: HEK-293 Cells Recombinant
EGFR vIII (EGFRv3) (AA 25-378) (Active) protein (His tag,FITC)EGFRv3 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
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- Application Notes
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 42.4 kDa.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, 0.5 % BSA, pH 7.4
- Storage
- -20 °C
- Storage Comment
- -20°C, avoid light
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- Target
- EGFRviii (EGFRv3) (EGFR vIII (EGFRv3))
- Alternative Name
- EGFRvIII (EGFRv3 Products)
- Background
- Synonyms:EGFRvIII,Description:The epidermal growth factor receptor (EGFR, ErbB-1, HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). Mutations affecting EGFR expression or activity could result in cancer. The type III EGF deletion-mutant receptor (EGFRvIII) is the most common mutation and was first identified in primary human glioblastoma tumors, EGFR gene amplification is correlated with the structural rearrangement of the gene. The EGFRvIII gene has an in-frame deletion of 801 base pairs, corresponding to exons 2-7 in the mRNA, resulting in the deletion of amino acids 30-297 in the extracellular domain and the generation of a glycine at the fusion point
- Molecular Weight
- 42.4 kDa
- NCBI Accession
- NP_001333870
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