LI Cadherin Protein (AA 450-777) (His tag)
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- Target See all LI Cadherin Proteins
- LI Cadherin
- Protein Type
- Recombinant
- Protein Characteristics
- AA 450-777
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This LI Cadherin protein is labelled with His tag.
- Purpose
- Human CDH17/Cadherin 17 Domain 5-7 Protein
- Sequence
- Glu450-Gly777
- Characteristics
- Recombinant Human CDH17/Cadherin 17 Domain 5-7 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu450-Gly777.
- Purity
- > 95 % as determined by Tris-Bis PAGE
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product LI Cadherin Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- LI Cadherin
- Alternative Name
- CDH17 (LI Cadherin Products)
- Synonyms
- CDH16 Protein, HPT-1 Protein, HPT1 Protein, HPT-1/LI Protein, cb903 Protein, fb65d02 Protein, wu:fb65d02 Protein, cadherin-17 Protein, cadherin 17 Protein, cadherin 17, LI cadherin (liver-intestine) Protein, CDH17 Protein, Cdh17 Protein, cdh17 Protein
- Background
- Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.
- Molecular Weight
- 36.79 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Tris-Bis PAGE result.
- UniProt
- Q12864
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