Leptin Protein (LEP)
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- Target See all Leptin (LEP) Proteins
- Leptin (LEP)
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purity
- 95 % (by SDS-PAGE and HPLC)
- Endotoxin Level
- Less than 0.1 ng/µg leptin.
- Top Product
- Discover our top product LEP Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Lyophilized leptin is poorly soluble at neutral pH. Add distilled water to reconstitute at 0.5 mg/ml.
- Buffer
- 0.5 mg leptin/ml in 10 mM sodium citrate, pH 4.0.
- Storage
- -20 °C
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- Target
- Leptin (LEP)
- Alternative Name
- Leptin (LEP Products)
- Synonyms
- ob Protein, obese Protein, LEPD Protein, OB Protein, OBS Protein, leptin Protein, Lep Protein, LEP Protein, lep Protein
- Background
- Leptin, the product of the obese gene, is a 16 kDa protein consisting of 146 amino acid residues. Leptin is produced in the adipose tissue, and is considered to play an important role in appetite control, fat metabolism and regulation of body weight. It targets the central nervous system, particularly hypothalamus, affecting food intake. Leptin levels are high in most obese individuals.
- Molecular Weight
- 16 kDa
- Pathways
- JAK-STAT Signaling, AMPK Signaling, Hormone Transport, Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Monocarboxylic Acid Catabolic Process
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