IL-11 Protein
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- Target See all IL-11 (IL11) Proteins
- IL-11 (IL11) (Interleukin 11 (IL11))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Sequence
- MPGPPPGPPR VSPDPRAELD STVLLTRSLL ADTRQLAAQL RDKFPADGDH NLDSLPTLAM SAGALGALQL PGVLTRLRAD LLSYLRHVQW LRRAGGSSLK TLEPELGTLQ ARLDRLLRRL QLLMSRLALP QPPPDPPAPP LAPPSSAWGG IRAAHAILGG LHLTLDWAVR GLLLLKTRL
- Characteristics
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Purified recombinant Human IL11 protein
Expression System: E.coli
Bioactivity: The ED50 was determined by the dose-dependent stimulation of the proliferation of Mouse T11 cells is ? 2.0 ng/mL, corresponding to a specific activity of ? 5 x 10^5 units/mg. - Purity
- > 98 % pure
- Endotoxin Level
- < 0.1 ng per µg (1 EU/µg) of IL-11.
- Top Product
- Discover our top product IL11 Protein
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Interleukin 11 (IL11) (AA 22-199) protein (His tag)
IL11 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 11 (IL11) (AA 22-199) protein (His tag)IL11 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 11 (IL11) (AA 22-199) (Active) protein (His tag)IL11 Origin: Human Host: Escherichia coli (E. coli) > 90 % AcA, CC Active
Interleukin 11 (IL11) (Active) proteinIL11 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Interleukin 11 (IL11) protein (Fc Tag)IL11 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Interleukin 11 (IL11) (AA 22-199) protein (His tag)IL11 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Interleukin 11 (IL11) (AA 1-199) protein (GST tag)IL11 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Interleukin 11 (IL11) (AA 25-74) protein (GST tag)IL11 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Interleukin 11 (IL11) proteinIL11 Origin: Human Host: Escherichia coli (E. coli) Recombinant
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute in 3 mM Tris, pH 8.0 at the stock concentration of 3 g/mL.
- Buffer
- Supplied as a lyophilized powder.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- Target
- IL-11 (IL11) (Interleukin 11 (IL11))
- Alternative Name
- IL11 (IL11 Products)
- Synonyms
- IL11 Protein, AGIF Protein, IL-11 Protein, Il-11 Protein, interleukin 11 Protein, IL11 Protein, Il11 Protein
- Background
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IL11 is a multifunctional cytokine produced by stromal cells such as fibroblasts, epithelial cells and osteoclasts. It is expressed in a wide variety of tissues including thymus, lung, bone, connective tissue and central nervous system. IL11 plays an important regulatory role in hematopoiesis by stimulating growth of myeloid, erythroid and megakaryocyte progenitor cells. It also regulates bone metabolism, inhibits production of proinflammatory cytokines and protects against gastromucosal injury.
Alternative Names: AGIF protein, IL-11 protein, IL-11, IL11, IL-11 protein, Interleukin 11 protein, Adipogenesis inhibitory factor protein, IL 11, IL 11 protein - Molecular Weight
- 19.1 kDa
- Pathways
- JAK-STAT Signaling, Negative Regulation of Hormone Secretion
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