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|Antigen||TYRO3 Protein Tyrosine Kinase (TYRO3) Antibodies|
|Reactivity||Human, Mouse (Murine) Alternatives|
|Conjugate||This TYRO3 antibody is un-conjugated Alternatives|
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
|5 references available|
|Supplier||Log in to see|
Product Details anti-TYRO3 AntibodyTarget Details TYRO3 Application Details Handling References for anti-TYRO3 antibody (ABIN359940) Images
|Specificity||This antibody reacts to TYRO3 (SKY).|
|Purification||Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS|
|Immunogen||This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human SKY.|
Target Details TYRO3Product Details anti-TYRO3 Antibody Application Details Handling References for anti-TYRO3 antibody (ABIN359940) Images back to top
|Alternative Name||TYRO3 (TYRO3 Antibody Abstract)|
|Background||Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.Synonyms: BYK, DTK, RSE, SKY, Tyrosine-protein kinase receptor TYRO3|
|Gene ID||7301, 9606|
Application DetailsProduct Details anti-TYRO3 Antibody Target Details TYRO3 Handling References for anti-TYRO3 antibody (ABIN359940) Images back to top
ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-TYRO3 Antibody Target Details TYRO3 Application Details References for anti-TYRO3 antibody (ABIN359940) Images back to top
|Buffer||PBS with 0.09 % (W/V) sodium azide|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
|Storage Comment||Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.|
References for anti-TYRO3 antibody (ABIN359940)Product Details anti-TYRO3 Antibody Target Details TYRO3 Application Details Handling Images back to top
Richard, Broux, Chiannilkulchai, Fougerousse, Allamand, Bourg, Brenguier, Devaud, Pasturaud, Roudaut: "Regional localization of human chromosome 15 loci." in: Genomics, Vol. 23, Issue 3, pp. 619-27, 1995
Crosier, Hall, Lewis, Morris, Wood, Morris, Crosier: "Isolation and characterization of the human DTK receptor tyrosine kinase." in: Growth factors (Chur, Switzerland), Vol. 11, Issue 2, pp. 137-44, 1995
Dai, Pan, Hassanain, Gupta, Murphy: "Molecular cloning of a novel receptor tyrosine kinase, tif, highly expressed in human ovary and testis." in: Oncogene, Vol. 9, Issue 3, pp. 975-9, 1994
Mark, Scadden, Wang, Gu, Goddard, Godowski: "rse, a novel receptor-type tyrosine kinase with homology to Axl/Ufo, is expressed at high levels in the brain." in: The Journal of biological chemistry, Vol. 269, Issue 14, pp. 10720-8, 1994
Ohashi, Mizuno, Kuma, Miyata, Nakamura: "Cloning of the cDNA for a novel receptor tyrosine kinase, Sky, predominantly expressed in brain." in: Oncogene, Vol. 9, Issue 3, pp. 699-705, 1994
ImagesProduct Details anti-TYRO3 Antibody Target Details TYRO3 Application Details Handling References for anti-TYRO3 antibody (ABIN359940) back to top