anti-Rat (Rattus) TNFAIP3 antibody for Immunohistochemistry

Recommended TNFAIP3 Antibody (supplied by: Log in to see )

Antigen
Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3) Antibodies
  • tnfaip3
  • MGC82339
  • TNFAIP3
  • A20
  • OTUD7C
  • TNFA1P2
  • Tnfip3
  • TNF alpha induced protein 3
  • TNF alpha induced protein 3 S homeolog
  • tumor necrosis factor, alpha-induced protein 3
  • TNFAIP3
  • tnfaip3.S
  • Tnfaip3
Reactivity
Mouse (Murine), Rat (Rattus), Human
110
69
67
6
2
1
1
Host
Rabbit
78
26
6
Clonality
Polyclonal
Conjugate
This TNFAIP3 antibody is un-conjugated
4
4
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
81
39
38
33
31
27
19
13
10
6
3
2
2
2
2
Options
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Pubmed
1 reference available

Available images

Immunofluorescence (IF) image for anti-Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3) antibody (ABIN3022985)
Western Blotting (WB) image for anti-Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3) antibody (ABIN3022985)
Catalog No. ABIN3022985
$ 393.25
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
15.863943 ABIN6265632 ELISA ICC IF IHC WB Rabbit IgG Log in to see Polyclonal 0
10 ABIN1875125 ICC IF IHC WB Rabbit IgG Log in to see Polyclonal 0
9.863943 ABIN604690 ELISA IHC IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal 0
9.863943 ABIN1030759 IHC ELISA WB Rabbit C-Term Log in to see Polyclonal 0
9.863943 ABIN1031138 IHC ELISA WB Rabbit Middle Region Log in to see Polyclonal 0
5.5 ABIN6673436 IHC WB Rabbit IgG Log in to see Polyclonal 1
4 ABIN478080 IHC ELISA WB Rabbit IgG Internal Region Log in to see Polyclonal 0
1 ABIN2574921 ICC IF IHC IHC (p) WB Rabbit Internal Region Log in to see Polyclonal 0
1 ABIN2880119 ICC IF IHC WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN2894550 IHC WB Rabbit Log in to see Polyclonal 0
1 ABIN1887667 IHC ELISA WB Rabbit Center Log in to see Polyclonal 0
1 ABIN1886989 IHC ELISA WB Rabbit C-Term Log in to see Polyclonal 0
1 ABIN2902986 ELISA IHC WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN1994956 IHC WB Rabbit IgG Log in to see 0
-0.92909527 ABIN4277012 ELISA ICC IF IHC IHC (p) WB Rabbit Center Log in to see Polyclonal 0
-3.9290953 ABIN4277013 ELISA ICC IF IHC IHC (p) WB Rabbit C-Term Log in to see Polyclonal 0

General

Antigen Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3) Antibodies
Reactivity Mouse (Murine), Rat (Rattus), Human
(110), (69), (67), (6), (2), (1), (1)
Host Rabbit
(78), (26), (6)
Clonality
Polyclonal
Conjugate This TNFAIP3 antibody is un-conjugated
(4), (4), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (IHC), Western Blotting (WB)
(81), (39), (38), (33), (31), (27), (19), (13), (10), (6), (3), (2), (2), (2), (2)
Pubmed 1 reference available
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Product Details anti-TNFAIP3 Antibody

Target Details TNFAIP3 Application Details Handling References for anti-TNFAIP3 antibody (ABIN3022985) Images
Purification Affinity purification
Immunogen Recombinant protein of human TNFAIP3
Isotype IgG
Plasmids, Primers & others

Target Details TNFAIP3

Product Details anti-TNFAIP3 Antibody Application Details Handling References for anti-TNFAIP3 antibody (ABIN3022985) Images back to top
Antigen
Alternative Name TNFAIP3 (TNFAIP3 Antibody Abstract)
Background A20, also referred to as TNF-alpha-induced protein 3 (TNFAIP3), is cytokine-inducible protein that functions to inhibit apoptosis and activate NF-kappaB. It was first identified as a TNF-alpha inducible primary response gene in human umbilical vein endothelial cells, and encodes a 790 AA protein containing seven Cys2/Cys2-zinc finger motifs. Constitutive expression of A20 is observed in lymphoid tissues , but it is transiently expressed in a variety of cell types in response to inflammatory signals such as TNF-alpha , IL-1 , phorbol esters , and LPS. Expression of A20 can confer resistance to apoptosis and NF-kappaB activation triggered by these signals, probably through interference with TRAF (TNF receptor associated factor) family members , and interaction with the NF-kappaB inhibiting protein ABIN. Studies also show that A20 contains site-specific ubiquitin modifying activity that can contribute to its biological functions. The amino-terminus of A20 contains de-ubiquitinating (DUB) activity for Lys63 branches, such as those found in TRAF6 and RIP, while the carboxyl-terminus contains ubiquitin ligase (E3) activity for Lys48 branches of the same substrates and leads to their degradation.
Synonyms: A20, MGC104522, MGC138687, MGC138688, OTUD7C, TNFA1P2
Gene ID 7128
UniProt P21580
Pathways TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Production of Molecular Mediator of Immune Response

Application Details

Product Details anti-TNFAIP3 Antibody Target Details TNFAIP3 Handling References for anti-TNFAIP3 antibody (ABIN3022985) Images back to top
Application Notes Recommended dilutions: WB: 1:500-1:2000, IHC: 1:50-1:200
Restrictions For Research Use only

Handling

Product Details anti-TNFAIP3 Antibody Target Details TNFAIP3 Application Details References for anti-TNFAIP3 antibody (ABIN3022985) Images back to top
Format Liquid
Buffer PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze / thaw cycles
Storage -20 °C/-80 °C

References for anti-TNFAIP3 antibody (ABIN3022985)

Product Details anti-TNFAIP3 Antibody Target Details TNFAIP3 Application Details Handling Images back to top
Product cited in:

He, Ma, Tian, Wei, Zhu, Li, Zhang, Wang, Zhang, Zhong: "ERRα negatively regulates type I interferon induction by inhibiting TBK1-IRF3 interaction." in: PLoS pathogens, Vol. 13, Issue 6, pp. e1006347, 2017 Method employed by authors: Western Blotting (WB)

Images

Product Details anti-TNFAIP3 Antibody Target Details TNFAIP3 Application Details Handling References for anti-TNFAIP3 antibody (ABIN3022985) back to top
Supplier Images
Immunofluorescence (IF) image for anti-Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3) antibody (ABIN3022985) Immunofluorescence analysis of U2OS cell using TNFAIP3 antibody. Blue: DAPI for nucle...
Western Blotting (WB) image for anti-Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3) antibody (ABIN3022985) Western blot analysis of extracts of various cell lines, using TNFAIP3 antibody.