anti-Human CD11b antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended CD11b Antibody (supplied by: Log in to see )

Antigen
Integrin alpha M (ITGAM) Antibodies
  • CD11b/CD18
  • CR3
  • CR3A
  • Cd11b
  • F730045J24Rik
  • Ly-40
  • MAC1
  • Mac-1
  • Mac-1a
  • CD11B
  • MAC-1
  • MAC1A
  • MO1A
  • SLEB6
  • C3bi
  • integrin subunit alpha M
  • integrin alpha M
  • integrin, alpha M (complement component 3 receptor 3 subunit)
  • integrin alpha-M
  • ITGAM
  • Itgam
  • LOC100351865
Epitope
AA 50-100
39
19
19
15
14
14
9
8
8
8
7
6
5
5
5
5
4
4
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
762
505
175
109
38
34
32
25
15
13
10
10
9
8
6
5
4
4
2
2
Host
Rabbit
540
417
160
17
5
2
Clonality
Polyclonal
Conjugate
This CD11b antibody is un-conjugated
146
127
97
64
19
17
17
16
14
14
14
13
12
11
9
9
9
8
8
7
6
6
5
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
937
276
226
200
169
169
91
91
90
61
26
21
13
12
9
8
5
5
4
3
3
2
1
1
1
1
1
1
1
1
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

Submit your validation data for this product and get a full refund. I want to validate this product

Learn more

Available images

Catalog No. ABIN730918
$ 318.45
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
13.144629 ABIN951175 EIA FACS IHC (p) WB Rabbit Ig Fraction AA 256-286, N-Term Log in to see Polyclonal 2
13.144629 ABIN4289454 IHC IHC (p) WB Mouse IgG1 Log in to see CL1719 0
13.144629 ABIN4289475 IHC IHC (p) WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN409930 FACS ICC IF IHC IHC (fro) IHC (p) SimWes WB Rabbit Internal Region, AA 250-350 Log in to see Polyclonal 25
1 ABIN2688906 BR IHC (fro) FACS IHC (p) IP WB Rat IgG2b, kappa Log in to see M1-70 8
1 ABIN258322 ICC FACS IF IHC (p) IHC WB Rabbit Internal Region, AA 500-600 Log in to see Polyclonal 17
1 ABIN118146 FACS IHC (fro) IF IHC (p) IP WB Rat IgG2b Log in to see M1-70-15 18
1 ABIN3043258 IHC (p) WB Rabbit IgG AA 17-382 Log in to see Polyclonal 3
1 ABIN118145 FACS IHC (fro) IHC (p) IP Rat IgG2b Log in to see M1-70 14
1 ABIN654625 FACS IHC (p) WB Rabbit Ig Fraction AA 253-282, N-Term Log in to see Polyclonal 1
1 ABIN4289448 FACS ICC IF IHC (fro) IHC (p) WB Alexa Fluor 488 Rabbit AA 250-350, Internal Region Log in to see Polyclonal 1
1 ABIN573960 FACS IHC IHC (fro) IHC (p) IP Rat IgG2b Log in to see M1-70-15 0
1 ABIN5533868 FACS IHC (p) WB Rabbit Ig Fraction AA 253-282, N-Term Log in to see Polyclonal 0
1 ABIN1177001 BR IHC (fro) FACS IHC (p) IP WB Rat IgG2b, kappa Log in to see M1-70 8
1 ABIN5665684 FACS IHC IHC (fro) IHC (p) IP Rat IgG2b Log in to see M1-70-15 0
1 ABIN1732800 FACS ICC IF IHC (p) WB Rabbit Internal Region, AA 250-350 Log in to see Polyclonal 0
1 ABIN4289459 FACS ICC IF IHC (fro) IHC (p) Alexa Fluor 488 Rat IgG2b Log in to see M1-70-15 0
1 ABIN5553276 EIA IHC (p) WB Goat Internal Region Log in to see Polyclonal 0
1 ABIN319553 Func FACS IHC (fro) IHC (p) IP Rat IgG2b Log in to see M1-70-15 6
1 ABIN1724066 IHC (fro) FACS IHC (p) IP Rat IgG2b Log in to see M1-70-15 0

General

Antigen Integrin alpha M (ITGAM) Antibodies
Epitope AA 50-100
(39), (19), (19), (15), (14), (14), (9), (8), (8), (8), (7), (6), (5), (5), (5), (5), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(762), (505), (175), (109), (38), (34), (32), (25), (15), (13), (10), (10), (9), (8), (6), (5), (4), (4), (2), (2)
Host Rabbit
(540), (417), (160), (17), (5), (2)
Clonality
Polyclonal
Conjugate This CD11b antibody is un-conjugated
(146), (127), (97), (64), (19), (17), (17), (16), (14), (14), (14), (13), (12), (11), (9), (9), (9), (8), (8), (7), (6), (6), (5), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(937), (276), (226), (200), (169), (169), (91), (91), (90), (61), (26), (21), (13), (12), (9), (8), (5), (5), (4), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Pubmed 8 references available
Supplier Log in to see

Product Details anti-CD11b Antibody

Target Details CD11b Application Details Handling References for anti-CD11b antibody (ABIN730918) Images
Specificity The immunogen of this product has partial sequence similarity to CD11d and may cross react.
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human CD11b
Isotype IgG
Plasmids, Primers & others

Target Details CD11b

Product Details anti-CD11b Antibody Application Details Handling References for anti-CD11b antibody (ABIN730918) Images back to top
Antigen
Alternative Name CD11b/c (ITGAM Antibody Abstract)
Background

Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain.

Subcellular location: Extracellular

Synonyms: CR3A, MO1A, CD11B, MAC-1, MAC1A, SLEB6, Integrin alpha-M, CD11 antigen-like family member B, CR-3 alpha chain, Cell surface glycoprotein MAC-1 subunit alpha, Leukocyte adhesion receptor MO1, Neutrophil adherence receptor, ITGAM, Integrin alpha-X, ITGAX, CD11 antigen-like family member C, Leu M5, Leukocyte adhesion glycoprotein p150,95 alpha chain, Leukocyte adhesion receptor p150,95, CD11c

Gene ID 3684
UniProt P11215
Pathways Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation

Application Details

Product Details anti-CD11b Antibody Target Details CD11b Handling References for anti-CD11b antibody (ABIN730918) Images back to top
Application Notes WB 1:100-1000
FCM 1:20-100
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only

Handling

Product Details anti-CD11b Antibody Target Details CD11b Application Details References for anti-CD11b antibody (ABIN730918) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

References for anti-CD11b antibody (ABIN730918)

Product Details anti-CD11b Antibody Target Details CD11b Application Details Handling Images back to top
Product cited in:

Yamaguchi, Sato, Kato-Itoh, Goto, Hara, Sanbo, Mizuno, Kobayashi, Yanagida, Umino, Ota, Hamanaka, Masaki, Rashid, Hirabayashi, Nakauchi: "Interspecies organogenesis generates autologous functional islets." in: Nature, Vol. 542, Issue 7640, pp. 191-196, 2017 Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Mouse (Murine)). Further details: Sample: pancreas

Velázquez, Enos, McClellan, Cranford, Chatzistamou, Singh, Nagarkatti, Nagarkatti, Fan, Murphy: "MicroRNA-155 deletion promotes tumorigenesis in the azoxymethane-dextran sulfate sodium model of colon cancer." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 310, Issue 6, pp. G347-58, 2016 Method employed by authors: Western Blotting (WB) (Sample species: Mouse (Murine)). Further details: Sample: colon

Kobayashi, Tanizaki, Kimura, Ishida, Nosaka, Toujima, Kuninaka, Minami, Ino, Kondo: "AG490, a Jak2 inhibitor, suppressed the progression of murine ovarian cancer." in: European journal of pharmacology, Vol. 766, pp. 63-75, 2015 Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Mouse (Murine)).

Zhang, Hu, Liu, Ye, Gui, Zhou, Qi, He, Wang, Wang: "CD11b deficiency suppresses intestinal tumor growth by reducing myeloid cell recruitment." in: Scientific reports, Vol. 5, pp. 15948, 2015 Method employed by authors: Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (Sample species: Mouse (Murine)). Further details: Sample: intestines

Liu, Xie, Ma, Zhang, Liang, Shi, Yu, Feng, Zhang, Wu: "Gr-1+CD11b+ cells facilitate Lewis lung cancer recurrence by enhancing neovasculature after local irradiation." in: Scientific reports, Vol. 4, pp. 4833, 2014 Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Mouse (Murine)).

Yu, Yang, Wang, Chen, Lu, Luo, Wang: "Ethanol supports macrophage recruitment and reinforces invasion and migration of lewis lung carcinoma." in: Alcoholism, clinical and experimental research, Vol. 38, Issue 10, pp. 2597-606, 2014 Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Mouse (Murine)).

Long, Qiu, Wang, Yang, Jia, Xin, Wang, Han, Fei, Liu: "Genetically engineered bone marrow mesenchymal stem cells improve functional outcome in a rat model of epilepsy." in: Brain research, Vol. 1532, pp. 1-13, 2013 (Sample species: Rat (Rattus)).

Long, Qiu, Liu, Fei, Feng, Wang, Zhong, Yi, Liu, Zhang, Han: "Functional recovery and neuronal regeneration of a rat model of epilepsy by transplantation of Hes1-down regulated bone marrow stromal cells." in: Neuroscience, Vol. 212, pp. 214-24, 2012

Images

Product Details anti-CD11b Antibody Target Details CD11b Application Details Handling References for anti-CD11b antibody (ABIN730918) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Integrin alpha M (ITGAM) (AA 50-100) antibody (ABIN730918) Formalin-fixed and paraffin embedded mouse brain tissue labeled with Anti-CD11b/Integ...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Integrin alpha M (ITGAM) (AA 50-100) antibody (ABIN730918) Formalin-fixed and paraffin embedded mouse brain tissue labeled with Anti-CD11b/Integ...
Flow Cytometry (FACS) image for anti-Integrin alpha M (ITGAM) (AA 50-100) antibody (ABIN730918) Human U937 cells probed with CD11b/c Polyclonal Antibody, Unconjugated ) (0.2ug) for...
Western Blotting (WB) image for anti-Integrin alpha M (ITGAM) (AA 50-100) antibody (ABIN730918) This image was kindly submitted by Kandy Velazquez from USC School of Medicine. Mouse...