anti-Pig (Porcine) AIFM1 antibody for Immunofluorescence (Paraffin-embedded Sections)

Recommended AIFM1 Antibody (supplied by: Log in to see )

Antigen
Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) Antibodies
  • aif
  • pdcd8
  • PDCD8
  • AIFM1
  • AIF
  • PCD8
  • CG7263
  • DmAIF
  • Dmel\\CG7263
  • GB16024
  • DDBDRAFT_0187853
  • DDBDRAFT_0191137
  • DDB_0187853
  • DDB_0191137
  • AIFsh2
  • Hq
  • Pdcd8
  • mAIF
  • Aif
  • zgc:91994
  • CMTX4
  • COWCK
  • COXPD6
  • apoptosis-inducing factor, mitochondrion-associated, 1
  • Apoptosis inducing factor
  • apoptosis inducing factor
  • allograft inflammatory factor 1
  • apoptosis-inducing factor, mitochondrion-associated 1
  • aifm1
  • AIFM1
  • AIF
  • aif
  • AIF1
  • Aifm1
Epitope
AA 130-180
28
14
14
13
10
5
4
4
4
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Pig (Porcine), Rat (Rattus)
179
77
74
19
11
10
6
4
3
3
2
1
1
1
1
1
1
1
Host
Rabbit
139
33
6
2
Clonality
Polyclonal
Conjugate
This AIFM1 antibody is un-conjugated
4
4
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
157
63
51
35
27
19
12
12
10
6
5
3
3
2
Options
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Catalog No. ABIN724010
$ 307.45
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN881968 IF (p) Alexa Fluor 350 Rabbit IgG AA 130-180 Log in to see Polyclonal
1 ABIN881966 IF (p) Alexa Fluor 488 Rabbit IgG AA 130-180 Log in to see Polyclonal
1 ABIN881969 IF (p) Alexa Fluor 555 Rabbit IgG AA 130-180 Log in to see Polyclonal
1 ABIN2809557 IF (p) Alexa Fluor 594 Rabbit IgG AA 130-180 Log in to see Polyclonal
1 ABIN881962 IF (p) Alexa Fluor 647 Rabbit IgG AA 130-180 Log in to see Polyclonal
1 ABIN724013 IF (p) Cy3 Rabbit IgG AA 130-180 Log in to see Polyclonal
1 ABIN724014 IF (p) Cy5 Rabbit IgG AA 130-180 Log in to see Polyclonal
1 ABIN724015 IF (p) Cy5.5 Rabbit IgG AA 130-180 Log in to see Polyclonal
1 ABIN724016 IF (p) Cy7 Rabbit IgG AA 130-180 Log in to see Polyclonal
1 ABIN724017 IF (p) FITC Rabbit IgG AA 130-180 Log in to see Polyclonal
1 ABIN4996244 IF (p) Alexa Fluor 680 Rabbit IgG AA 130-180 Log in to see Polyclonal
1 ABIN4996245 IF (p) Alexa Fluor 750 Rabbit IgG AA 130-180 Log in to see Polyclonal

Top referenced anti-AIFM1 antibody for Immunofluorescence (Paraffin-embedded Sections)

  • Human Polyclonal AIFM1 Primary Antibody for IF (p), IHC (p) - ABIN724010 (1 Publications): Gong, Hua, Zhang, Zhao, Tang, Mei, Zhang, Cui, Li: Hypothermia-induced neuroprotection is associated with reduced mitochondrial membrane permeability in a swine model of cardiac arrest. in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2013 (PubMed)

Similar anti-AIFM1 Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus) Pig (Porcine)
Immunofluorescence (fixed cells) (IF/ICC) 5 Antibodies 3 Antibodies 3 Antibodies
Simple Western (SimWes) 2 Antibodies 2 Antibodies 2 Antibodies
Western Blotting (WB) 157 Antibodies 64 Antibodies 61 Antibodies 8 Antibodies
Immunoprecipitation (IP) 10 Antibodies 8 Antibodies 8 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 36 Antibodies 18 Antibodies 18 Antibodies 3 Antibodies
Immunohistochemistry (IHC) 50 Antibodies 25 Antibodies 27 Antibodies

General

Antigen Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) Antibodies
Epitope AA 130-180
(28), (14), (14), (13), (10), (5), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Pig (Porcine), Rat (Rattus)
(179), (77), (74), (19), (11), (10), (6), (4), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1)
Host Rabbit
(139), (33), (6), (2)
Clonality
Polyclonal
Conjugate This AIFM1 antibody is un-conjugated
(4), (4), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(157), (63), (51), (35), (27), (19), (12), (12), (10), (6), (5), (3), (3), (2)
Pubmed 1 reference available
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Product Details anti-AIFM1 Antibody

Target Details AIFM1 Application Details Handling ProductDetails: References for anti-AIFM1 antibody (ABIN724010) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human AIF
Isotype IgG

Target Details AIFM1

Product Details anti-AIFM1 Antibody Application Details Handling ProductDetails: References for anti-AIFM1 antibody (ABIN724010) Images back to top
Antigen
Alternative Name AIF (AIFM1 Antibody Abstract)
Background

Functions both as NADH oxidoreductase and as regulator of apoptosis. In response to apoptotic stimuli, it is released from the mitochondrion intermembrane space into the cytosol and to the nucleus, where it functions as a proapoptotic factor in a caspase-independent pathway. In contrast, functions as an antiapoptotic factor in normal mitochondria via its NADH oxidoreductase activity. The soluble form (AIFsol) found in the nucleus induces 'parthanatos' i.e. caspase-independent fragmentation of chromosomal DNA. Interacts with EIF3G,and thereby inhibits the EIF3 machinery and protein synthesis, and activates casapse-7 to amplify apoptosis. Plays a critical role in caspase-independent, pyknotic cell death in hydrogen peroxide-exposed cells. Binds to DNA in a sequence-independent manner.

Subcellular location: Cytoplasm, Mitochondrion

Synonyms: AIF, CMT2D, CMTX4, COWCK, NADMR, NAMSD, PDCD8, COXPD6, Apoptosis-inducing factor 1, mitochondrial, Programmed cell death protein 8, AIFM1

Gene ID 9131
UniProt O95831
Research Area Cancer, Apoptosis/Necrosis, Cell Cycle
Pathways Apoptosis, Positive Regulation of Endopeptidase Activity, Cell RedoxHomeostasis, Smooth Muscle Cell Migration

Application Details

Product Details anti-AIFM1 Antibody Target Details AIFM1 Handling ProductDetails: References for anti-AIFM1 antibody (ABIN724010) Images back to top
Application Notes WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only

Handling

Product Details anti-AIFM1 Antibody Target Details AIFM1 Application Details ProductDetails: References for anti-AIFM1 antibody (ABIN724010) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

ProductDetails: References for anti-AIFM1 antibody (ABIN724010)

Product Details anti-AIFM1 Antibody Target Details AIFM1 Application Details Handling Images back to top
Product cited in:

Gong, Hua, Zhang, Zhao, Tang, Mei, Zhang, Cui, Li: "Hypothermia-induced neuroprotection is associated with reduced mitochondrial membrane permeability in a swine model of cardiac arrest." in: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, Vol. 33, Issue 6, pp. 928-34, 2013 (1:400).

Images

Product Details anti-AIFM1 Antibody Target Details AIFM1 Application Details Handling ProductDetails: References for anti-AIFM1 antibody (ABIN724010) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-AIFM1 antibody (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1) (AA 130-180) (ABIN724010) Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti-AIF Polyclona...
Immunofluorescence (IF) image for anti-AIFM1 antibody (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1) (AA 130-180) (ABIN724010) Formalin-fixed and paraffin embedded labeled with human gastric carcinoma Rabbit Anti...
Immunofluorescence (IF) image for anti-AIFM1 antibody (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1) (AA 130-180) (ABIN724010) Formalin-fixed and paraffin embedded labeled with human gastric carcinoma Rabbit Anti...
Immunohistochemistry (IHC) image for anti-AIFM1 antibody (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1) (AA 130-180) (ABIN724010) Formalin-fixed and paraffin embedded human cervical tissue labeled with Anti-AIF Poly...
Western Blotting (WB) image for anti-AIFM1 antibody (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1) (AA 130-180) (ABIN724010) HT1080 lysates probed with Anti-AIF Polyclonal Antibody at 1:5000 for 90 min at 37˚C.
Western Blotting (WB) image for anti-AIFM1 antibody (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1) (AA 130-180) (ABIN724010) Mouse Liver lysates probed with AIF Polyclonal Antibody, unconjugated at 1:300 overn...
Western Blotting (WB) image for anti-AIFM1 antibody (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1) (AA 130-180) (ABIN724010) K562 lysates probed with AIF Polyclonal Antibody, unconjugated at 1:300 overnight at...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-AIFM1 antibody (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1) (AA 130-180) (ABIN724010) Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti-AIF Polyclona...
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) image for anti-AIFM1 antibody (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1) (AA 130-180) (ABIN724010) Formalin-fixed and paraffin embedded labeled with human gastric carcinoma Rabbit Anti...
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) image for anti-AIFM1 antibody (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1) (AA 130-180) (ABIN724010) Formalin-fixed and paraffin embedded labeled with human gastric carcinoma Rabbit Anti...