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TNFRSF18 encodes a member of the TNF-receptor superfamily. Additionally we are shipping TNFRSF18 Proteins (41) and TNFRSF18 Kits (19) and many more products for this protein.
Showing 10 out of 355 products:
Human Monoclonal TNFRSF18 Primary Antibody for FACS - ABIN4896951
Godfrey, Spoden, Ge, Baker, Liu, Levine, June, Blazar, Porter: Cord blood CD4(+)CD25(+)-derived T regulatory cell lines express FoxP3 protein and manifest potent suppressor function. in Blood 2005
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Mouse (Murine) Monoclonal TNFRSF18 Primary Antibody for BR, FACS - ABIN1176970
Nocentini, Giunchi, Ronchetti, Krausz, Bartoli, Moraca, Migliorati, Riccardi: A new member of the tumor necrosis factor/nerve growth factor receptor family inhibits T cell receptor-induced apoptosis. in Proceedings of the National Academy of Sciences of the United States of America 1997
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Mouse (Murine) Monoclonal TNFRSF18 Primary Antibody for CyTOF, FACS - ABIN4898962
Dobrzynski, Fitzgerald, Cao, Mingozzi, Wang, Herzog: Prevention of cytotoxic T lymphocyte responses to factor IX-expressing hepatocytes by gene transfer-induced regulatory T cells. in Proceedings of the National Academy of Sciences of the United States of America 2006
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Human Monoclonal TNFRSF18 Primary Antibody for FACS - ABIN4896943
Tuyaerts, Van Meirvenne, Bonehill, Heirman, Corthals, Waldmann, Breckpot, Thielemans, Aerts: Expression of human GITRL on myeloid dendritic cells enhances their immunostimulatory function but does not abrogate the suppressive effect of CD4+CD25+ regulatory T cells. in Journal of leukocyte biology 2007
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Human Monoclonal TNFRSF18 Primary Antibody for FACS - ABIN4896945
Mandapathil, Hilldorfer, Szczepanski, Czystowska, Szajnik, Ren, Lang, Jackson, Gorelik, Whiteside: Generation and accumulation of immunosuppressive adenosine by human CD4+CD25highFOXP3+ regulatory T cells. in The Journal of biological chemistry 2010
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Human Monoclonal TNFRSF18 Primary Antibody for FACS, ELISA - ABIN610275
Ohmstede, Bland, Merrill, Sahyoun: Relationship of genes encoding Ca2+/calmodulin-dependent protein kinase Gr and calspermin: a gene within a gene. in Proceedings of the National Academy of Sciences of the United States of America 1991
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Human Monoclonal TNFRSF18 Primary Antibody for FACS, ELISA - ABIN610272
Derkinderen, Toutant, Kadaré, Ledent, Parmentier, Girault: Dual role of Fyn in the regulation of FAK+6,7 by cannabinoids in hippocampus. in The Journal of biological chemistry 2001
Human Monoclonal TNFRSF18 Primary Antibody for FACS, ELISA - ABIN610416
Fallon, Moreau, Croft, Labib, Gu, Fon: Parkin and CASK/LIN-2 associate via a PDZ-mediated interaction and are co-localized in lipid rafts and postsynaptic densities in brain. in The Journal of biological chemistry 2002
Human Monoclonal TNFRSF18 Primary Antibody for FACS, ELISA - ABIN610418
Brouet, Sonveaux, Dessy, Balligand, Feron: Hsp90 ensures the transition from the early Ca2+-dependent to the late phosphorylation-dependent activation of the endothelial nitric-oxide synthase in vascular endothelial growth factor-exposed endothelial cells. in The Journal of biological chemistry 2001
These results suggest that therapeutically targeting GITR represents a unique approach to cancer immunotherapy and suggests that a multimeric fusion protein may provide increased agonistic potential versus an antibody
These findings support further study into combination partners for GITRL (show TNFSF18 Antibodies)-FP that may augment CD8 (show CD8A Antibodies) T-cell priming as well as provide hypotheses that can be tested in human clinical trials exploring GITR agonists including GITRL (show TNFSF18 Antibodies)-FP.
Expression of human GITR was comparable with that of mouse GITR in tumor-infiltrating Tregs despite being drastically lower in other human TILs and in many human peripheral blood populations.
anti-GITR mAb shifts Treg populations to enable immune attack on tumors, with clinical implications for molecular markers to modify emerging treatments.
Continuous GITR stimulation through B cell Gitrl (show TNFSF18 Antibodies) acts protective in a mouse model of atherosclerosis by regulating the balance between regulatory and effector memory CD4 (show CD4 Antibodies)(+) T cells.
these results indicate that blockade of GITR signaling can ameliorate arthritis progression mainly by modulating the follicular helper T cell response
GITR appears as a potential target for intervention during infection by the parasite Toxoplasma gondii, even though further studies are still necessary to better characterize the immune response triggered by GITR activation during T. gondii infection
our data suggest a critical role for GITR in Treg cell homeostasis and indicate that Ptpn22 (show PTPN22 Antibodies) independently affects the differentiation status of Treg cells and their homeostatic behavior
These findings provide further support for the continued development of agonist anti-GITR antibodies as an immunotherapeutic strategy for osteosarcoma. We suggest that our proposed immunotherapy could be developed further to improve osteosarcoma treatment
Th9 cells and iTregs are developmentally linked and GITR can subvert tolerogenic conditions to boost Th9 immunity.
HTLV-1 infection can modify the expression of main functional transcription factors, FOXP3 (show FOXP3 Antibodies) and GITR
a novel molecular mechanism by which MBD4 (show MBD4 Antibodies) inhibits GITR expression in a DNMT1 (show DNMT1 Antibodies)-dependent manner
Aberrant expression of GITR may contribute to systemic lupus erithematosus pathogenesis. Glucocorticoid may achieve its therapeutic effect partly by inducing GITR expression on Tresps rather than Tregs, which initiates the apoptosis of Tresp cells in SLE patients.
GITR expression can enhance the sensitivity to Bortezomib by inhibiting Bortezomib-induced NF-kappaB (show NFKB1 Antibodies) activation.
GITR is a crucial player in differentiation of thymic regulatory T cells and expansion of regulatory T cells, including both thymic regulatory T cells and peripheral regulatory T cells.
Data may suggest a key role of regulatory GITR+CD25 (show IL2RA Antibodies) low/-CD4 (show CD4 Antibodies)+ T cells subset in the modulation of the abnormal immune response in lupus erythematosus (SLE) patients.
results suggest that the GITR rs3753348 polymorphism may be involved in the development and susceptibility of CWP.
these results show a higher susceptibility to apoptosis in patients' versus controls' T(reg (show EXTL3 Antibodies)) cells, suggesting that GITR is a T(reg (show EXTL3 Antibodies))-cell marker that would be primarily involved in T(reg (show EXTL3 Antibodies))-cell survival rather than in their suppressor function.
Our findings indicate the possible involvement of GITR-GITRL (show TNFSF18 Antibodies) pathway in the pathogenesis of pSS (show CDSN Antibodies).
GITR acts as a potential tumor suppressor in MM.
This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
tumor necrosis factor receptor superfamily member 18
, glucocorticoid-induced TNFR-related
, tumor necrosis factor receptor superfamily, member 18
, glucocorticoid-induced TNFR-related protein
, TNF receptor superfamily activation-inducible protein
, activation-inducible TNFR family receptor