Integrin beta 2 antibody (Biotin)
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- Target See all Integrin beta 2 (ITGB2) Antibodies
- Integrin beta 2 (ITGB2)
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Reactivity
- Rat
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Integrin beta 2 antibody is conjugated to Biotin
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Application
- Flow Cytometry (FACS)
- Specificity
- Rat CD18 (LFA-1 chain).
- Clone
- WT-3
- Isotype
- IgG1
- Top Product
- Discover our top product ITGB2 Primary Antibody
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- Restrictions
- For Research Use only
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- Concentration
- 0.1 mg/ml
- Storage
- 4 °C
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- Target
- Integrin beta 2 (ITGB2)
- Alternative Name
- CD18 (LFA-1 Chain) (ITGB2 Products)
- Synonyms
- CD18 antibody, LAD antibody, LCAMB antibody, LFA-1 antibody, MAC-1 antibody, MF17 antibody, MFI7 antibody, 2E6 antibody, AI528527 antibody, Cd18 antibody, Lfa1 antibody, ITGB2 antibody, itgb2 antibody, itgb2-a antibody, itgb2-b antibody, integrin subunit beta 2 antibody, integrin beta 2 antibody, integrin subunit beta 2 S homeolog antibody, ITGB2 antibody, Itgb2 antibody, itgb2.S antibody
- Background
- LFA-1 (lymphocyte function associated molecule-1) is one of the leukocyte integrins. It is a heterodimer consisting of and subunits of 160-170 kDa and 95-100 kDa respectively. LFA-1 promotes non-antigen dependent adhesion of T-cells to a variety of lymphoid cells that bear its complementary receptor I-CAM-1 (1). It has a broad distribution and is found on most common lymphocytes. ABIN133277is specific for the subunit of LFA-1. This antibody also recognizes MAC-1 and p150, 95 as well as LFA-1, since they all contain the same subunit. It inhibits homeotypic aggregation of PHA blasts and blocks the binding of rat lymphocytes to purified rat ICAM-1 (1). Applications include immunoprecipitation, flow cytometric analysis and immunohistochemistry, cryostat sections, and in vivo/in vitro functional studies (1,2,3).
- Pathways
- NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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