MDM2 antibody (Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse)) (AA 177-195)

Details for Product anti-MDM2 Antibody No. ABIN2475550
Antigen
  • ACTFS
  • HDMX
  • hdm2
  • zgc:109834
  • 1700007J15Rik
  • AA415488
  • Mdm-2
  • MDM2 proto-oncogene
  • MDM2 proto-oncogene S homeolog
  • Mdm2, p53 E3 ubiquitin protein ligase homolog (mouse)
  • MDM2 oncogene, E3 ubiquitin protein ligase
  • transformed mouse 3T3 cell double minute 2
  • MDM2
  • mdm2.S
  • Mdm2
  • mdm2
Epitope
AA 177-195
42
39
35
34
24
24
23
20
17
15
13
13
11
11
6
5
5
4
4
4
4
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Mouse (Murine)
428
172
112
22
5
2
2
2
1
1
Host
Rabbit
352
84
7
1
Clonality
Polyclonal
Conjugate
This MDM2 antibody is un-conjugated
17
12
12
10
10
10
7
7
7
7
7
7
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
ELISA, Western Blotting (WB)
303
164
154
87
76
39
27
26
22
19
12
12
7
5
4
4
2
1
1
1
Options
Immunogen Synthetic peptide corresponding to aa 177-195 of mouse Mdm2.
Isotype IgG
Characteristics Purified IgG
Purification Purified
Plasmids, Primers & others Plasmids, Primers & others MDM2 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name MDM2 (MDM2 Antibody Abstract)
Gene ID 17246
UniProt P23804
Pathways p53 Signaling, PI3K-Akt Signaling, Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Autophagy
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Product cited in: Sdek, Ying, Zheng, Margulis, Tang, Tian, Xiao: "The central acidic domain of MDM2 is critical in inhibition of retinoblastoma-mediated suppression of E2F and cell growth." in: The Journal of biological chemistry, Vol. 279, Issue 51, pp. 53317-22, 2004 (PubMed).

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