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Integrin beta 2 antibody
ITGB2
Reactivity: Human, Pig, Rhesus Monkey, Rabbit, Cynomolgus
FACS
Host: Mouse
Monoclonal
6-7
unconjugated
Product Details anti-Integrin beta 2 Antibody
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Target
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Integrin beta 2 (ITGB2)
Reactivity
All reactivities for Integrin beta 2 antibodies
Human, Pig, Rhesus Monkey, Rabbit, Cynomolgus
Host
All hosts for Integrin beta 2 antibodies
Mouse
Clonality
All clonalities for Integrin beta 2 antibodies
Monoclonal
Conjugate
All conjugates for Integrin beta 2 antibodies
This Integrin beta 2 antibody is un-conjugated
Application
All applications for Integrin beta 2 antibodies
Flow Cytometry (FACS)
Brand
BD Pharmingen™
Characteristics
Reacts with β2 integrin, a 90-95 kDa transmembrane protein, which associates non-covalently as a heterodimer with the a chains of CD11a, CD11b, or CD11c. CD18 is expressed on lymphocytes, monocytes, and more weakly on granulocytes. LFA-1 has been shown to play an important role in homotypic and heterotypic cellular adhesion in immune and inflammatory responses. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of peripheral blood lymphocytes analyzed by flow cytometry BD Pharmingen™ Purified Mouse Anti-Human CD18 - Purified - Clone 6.7 - Isotype Mouse IgG1, κ - Reactivity Hu, Cyno, Pig, Rab, Rhe - 0.1 mg
Purification
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Clone
6-7
Isotype
IgG1 kappa
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Aqueous buffered solution containing ≤0.09 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
Store undiluted at 4°C.
Target Details for Integrin beta 2
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Target
Integrin beta 2 (ITGB2)
Alternative Name
CD18 (ITGB2 Products )
Synonyms
CD18 antibody, LAD antibody, LCAMB antibody, LFA-1 antibody, MAC-1 antibody, MF17 antibody, MFI7 antibody, 2E6 antibody, AI528527 antibody, Cd18 antibody, Lfa1 antibody, ITGB2 antibody, itgb2 antibody, itgb2-a antibody, itgb2-b antibody, integrin subunit beta 2 antibody, integrin beta 2 antibody, integrin subunit beta 2 S homeolog antibody, ITGB2 antibody, Itgb2 antibody, itgb2.S antibody
Background
Synonyms: Integrin β2 chain
Pathways
NF-kappaB Signaling , Activation of Innate immune Response , Toll-Like Receptors Cascades , Activated T Cell Proliferation
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