C-MYC antibody (V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian)) (AA 408-439)

Details for Product anti-MYC Antibody No. ABIN3026175, Supplier: Log in to see
Antigen
  • MRTL
  • MYCC
  • bHLHe39
  • c-Myc
  • CMYC
  • c-myc
  • C-MYC
  • LOC100136746
  • RNCMYC
  • mMyc
  • AU016757
  • Myc2
  • Niard
  • Nird
  • MYC
  • cmyc
  • zc-myc
  • c-myc II
  • myc-B
  • myc2
  • CMyc
  • CG10798
  • D-Myc
  • DM
  • DMYc
  • Dm
  • Dmel\CG10798
  • Dmyc
  • EG:BACN5I9.1
  • anon-WO03040301.171
  • bHLHe57
  • c-MYC
  • d-myc
  • dMYC
  • dMyc
  • dMyc1
  • da
  • dm
  • dm/dMyc
  • dm/myc
  • dmyc
  • dmyc1
  • l(1)G0139
  • l(1)G0354
  • l(1)G0359
  • myc
  • MYC proto-oncogene, bHLH transcription factor
  • v-myc myelocytomatosis viral oncogene homolog
  • myelocytomatosis oncogene
  • MYC proto-oncogene, bHLH transcription factor a
  • MYC proto-oncogene, bHLH transcription factor L homeolog
  • v-myc myelocytomatosis viral oncogene homolog (avian)
  • CG10798 gene product from transcript CG10798-RB
  • MYC
  • LOC100136746
  • Myc
  • myca
  • myc.L
Alternatives
anti-Tag C-MYC antibody for Western Blotting
Epitope
AA 408-439
167
120
77
46
43
29
26
18
18
16
15
15
14
10
5
5
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Chimpanzee, Gorilla, Human
705
215
125
50
42
36
20
20
19
14
14
13
12
9
9
6
6
5
4
3
3
3
3
2
1
1
1
1
1
Host
Mouse
376
343
29
16
8
1
Clonality (Clone)
Monoclonal ()
Conjugate
This C-MYC antibody is un-conjugated
47
41
40
21
18
17
17
14
13
13
13
13
13
13
12
12
12
10
5
5
5
4
4
4
4
4
4
4
2
2
2
2
2
2
2
2
2
2
2
1
1
1
Application
Flow Cytometry (FACS), Immunofluorescence (IF)
485
246
231
227
227
162
151
123
92
52
19
14
14
11
10
8
6
6
4
2
2
1
Options
Supplier
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Supplier Product No.
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Immunogen Amino acids 408-439 (AEEQKLISEEDLLRKRREQLKHKLEQLRNSCA) from the human protein were used as the immunogen for this c-Myc antibody.
Clone MYC699
Isotype IgG1, kappa
No Cross-Reactivity Mouse (Murine)
Purification Protein G affinity chromatography
Alternative Name C-Myc (MYC Antibody Abstract)
Background The c-Myc protein is a transcription factor, which is encoded by the c-Myc gene on human chromosome 8q24. c-Myc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression. The phosphorylation of c-Myc has been investigated and previous studies have suggested a functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3, cyclin dependent kinase, ERK2 and C-Jun N terminal Kinase (JNK) in cell proliferation and cell cycle regulation. Studies also have shown that c-Myc is essential for tumor cell development in vasculogenesis and angiogenesis that distribute blood throughout the cells, and which brought extensive attention in the development of new therapeutic approach for cancer treatment.
Pathways p53 Signaling, Cell Division Cycle, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus
Application Notes The optimal dilution of the c-Myc antibody for each application should be determined by the researcher.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence (1-2 μg/mL)
Restrictions For Research Use only
Concentration 0.2 mg/mL
Buffer 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment Store the c-Myc antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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