×
For best experience we recommend to activate Javascript in your browser.
BRAF antibody (pThr598)
BRAF
Reactivity: Human
DB
Host: Rabbit
Polyclonal
RB10944
unconjugated
Product Details anti-BRAF Antibody
(hide)
Target
See all BRAF Antibodies
BRAF
(B-Raf proto-oncogene, serine/threonine kinase (BRAF))
Binding Specificity
All epitopes for BRAF antibodies
pThr598
Reactivity
All reactivities for BRAF antibodies
Human
Host
All hosts for BRAF antibodies
Rabbit
Clonality
All clonalities for BRAF antibodies
Polyclonal
Conjugate
All conjugates for BRAF antibodies
This BRAF antibody is un-conjugated
Application
All applications for BRAF antibodies
Dot Blot (DB)
Predicted Reactivity
C, M, B, Rat
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This BRAF Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T598 of human BRAF.
Clone
RB10944
Isotype
Ig Fraction
Top Product
Discover our top product BRAF Primary Antibody
Alternatives
(show)
Application Details
(hide)
Application Notes
DB: 1:500
Restrictions
For Research Use only
Handling
(hide)
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date
6 months
Target Details for BRAF
(hide)
Target
BRAF
(B-Raf proto-oncogene, serine/threonine kinase (BRAF))
Alternative Name
BRAF (BRAF Products )
Synonyms
B-RAF1 antibody, BRAF1 antibody, NS7 antibody, RAFB1 antibody, C-RMIL antibody, RMIL antibody, B-Raf antibody, braf1 antibody, rafb1 antibody, b-raf1 antibody, sierrabraf antibody, BRAF antibody, 9930012E13Rik antibody, AA120551 antibody, AA387315 antibody, AA473386 antibody, B-raf antibody, Braf-2 antibody, Braf2 antibody, C230098H17 antibody, C87398 antibody, D6Ertd631e antibody, braf antibody, fc48g01 antibody, wu:fc48g01 antibody, B-Raf proto-oncogene, serine/threonine kinase antibody, B-Raf proto-oncogene, serine/threonine kinase S homeolog antibody, Braf transforming gene antibody, si:dkey-222f8.3 antibody, BRAF antibody, Braf antibody, braf.S antibody, braf antibody, si:dkey-222f8.3 antibody
Background
BRAF is involved in the transduction of mitogenic signals from the cell membrane to the nucleus. It may play a role in the postsynaptic responses of hippocampal neuron. Defects in BRAF are a cause of cardiofaciocutaneous syndrome (CFC syndrome), and a wide range of cancers such as lung cancer, non-Hodgkins lymphoma, and colorectal cancer.
Molecular Weight
84437
Gene ID
673
NCBI Accession
NP_004324
UniProt
P15056
Pathways
MAPK Signaling , RTK Signaling , Neurotrophin Signaling Pathway , Ribonucleoprotein Complex Subunit Organization , Hepatitis C , Autophagy
Recently viewed
(hide)