SIGMAR1 antibody (N-Term)

Catalog No. ABIN543555

Product Details anti-SIGMAR1 Antibody

Target: SIGMAR1 (sigma Non-Opioid Intracellular Receptor 1 (SIGMAR1))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIGMAR1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of OPRS1.

Cross-Reactivity: Human

Immunogen: A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human OPRS1.

Application Details

Application Notes: Western Blot (1:1000)
Flow cytometry (1:10-50)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-SIGMAR1 antibody (ABIN543555)

Lee, Chen, Schetz et al.: "An unambiguous assay for the cloned human sigma1 receptor reveals high affinity interactions with dopamine D4 receptor selective compounds and a distinct structure-affinity relationship for ..." in: European journal of pharmacology, Vol. 578, Issue 2-3, pp. 123-36, (2008) (PubMed).

Cobos, del Pozo, Baeyens: "Irreversible blockade of sigma-1 receptors by haloperidol and its metabolites in guinea pig brain and SH-SY5Y human neuroblastoma cells." in: Journal of neurochemistry, Vol. 102, Issue 3, pp. 812-25, (2007) (PubMed).

Maurice, Grégoire, Espallergues: "Neuro(active)steroids actions at the neuromodulatory sigma1 (sigma1) receptor: biochemical and physiological evidences, consequences in neuroprotection." in: Pharmacology, biochemistry, and behavior, Vol. 84, Issue 4, pp. 581-97, (2006) (PubMed).

Target Details for SIGMAR1

Target: SIGMAR1 (sigma Non-Opioid Intracellular Receptor 1 (SIGMAR1))

Alternative Name: SIGMAR1 / OPRS1 (SIGMAR1 Products)

Synonyms: ALS16 antibody, OPRS1 antibody, SIG-1R antibody, SR-BP antibody, SR-BP1 antibody, SRBP antibody, sigma1R antibody, AL024364 antibody, Oprs1 antibody, mSigmaR1 antibody, Sigma1R antibody, oprs1 antibody, zgc:56378 antibody, sigma non-opioid intracellular receptor 1 antibody, sigma non-opioid intracellular receptor 1 L homeolog antibody, SIGMAR1 antibody, Sigmar1 antibody, sigmar1.L antibody, sigmar1 antibody

Gene ID: 10280

Pathways: SARS-CoV-2 Protein Interactome