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SIGMAR1 antibody (Middle Region)
SIGMAR1
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-SIGMAR1 Antibody
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Target
See all SIGMAR1 Antibodies
SIGMAR1
(sigma Non-Opioid Intracellular Receptor 1 (SIGMAR1))
Binding Specificity
All epitopes for SIGMAR1 antibodies
Middle Region
Reactivity
All reactivities for SIGMAR1 antibodies
Human
Host
All hosts for SIGMAR1 antibodies
Rabbit
Clonality
All clonalities for SIGMAR1 antibodies
Polyclonal
Conjugate
All conjugates for SIGMAR1 antibodies
This SIGMAR1 antibody is un-conjugated
Application
All applications for SIGMAR1 antibodies
Western Blotting (WB)
Sequence
AVEWGPNTWM VEYGRGVIPS TLAFALADTV FSTQDFLTLF YTLRSYARGL
Purification
Affinity purified
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human SIGMAR1
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for SIGMAR1
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Target
SIGMAR1
(sigma Non-Opioid Intracellular Receptor 1 (SIGMAR1))
Alternative Name
SIGMAR1 (SIGMAR1 Products )
Synonyms
ALS16 antibody, OPRS1 antibody, SIG-1R antibody, SR-BP antibody, SR-BP1 antibody, SRBP antibody, sigma1R antibody, AL024364 antibody, Oprs1 antibody, mSigmaR1 antibody, Sigma1R antibody, oprs1 antibody, zgc:56378 antibody, sigma non-opioid intracellular receptor 1 antibody, sigma non-opioid intracellular receptor 1 L homeolog antibody, SIGMAR1 antibody, Sigmar1 antibody, sigmar1.L antibody, sigmar1 antibody
Background
This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor, it is now thought to be a non-opioid receptor. Mutations in this gene has been associated with juvenile amyotrophic lateral sclerosis 16. Alternative splicing of this gene results in transcript variants encoding distinct isoforms. Alias Symbols: SRBP, ALS16, OPRS1, SR-BP, SIG-1R, SR-BP1, sigma1R, hSigmaR1 Protein Size: 223
Gene ID
10280
NCBI Accession
NM_001282205 , NP_001269134
UniProt
Q99720
Pathways
SARS-CoV-2 Protein Interactome
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