alpha Adaptin antibody

Catalog No. ABIN5958900

Product Details anti-alpha Adaptin Antibody

Target: alpha Adaptin (AP2A1) (Adaptor-Related Protein Complex 2, alpha 1 Subunit (AP2A1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This alpha Adaptin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Specificity: 100 kDa coated vesicle protein A,Adapter-related protein complex 2 alpha-1 subunit,adapter-related protein complex 2 subunit alpha-1,Adaptin alpha A,Adaptin alpha,Adaptor protein complex AP 2 alpha 1 subunit,adaptor protein complex AP 2 subunit alpha 1,Adaptor protein complex AP-2 subunit alpha-1,Adaptor protein complex AP2 alpha 1 subunit,adaptor protein complex AP2 subunit alpha 1,Adaptor related protein complex 2 alpha 1 subunit,Adaptor related protein complex AP 2 alpha 1 subunit,Adaptor related protein complex AP2 alpha 1 subunit,ADTAA,Alpha A adaptin,Alpha adaptin A,Alpha-adaptin A,alpha1 adaptin,Alpha1-adaptin,AP 2 alpha,AP 2 complex subunit alpha 1,AP-2 complex subunit alpha-1,AP2 complex subunit alpha 1,AP2-ALPHA,Ap2a1,AP2A1,CLAPA 1,CLAPA1,Clathrin adaptor complex AP2. alpha subunit,Clathrin assembly protein complex 2 alpha A large chain,Clathrin assembly protein complex 2 alpha-A large chain,Clathrin associated / assembly / adaptor protein large alpha 1,clathrin associated assembly adaptor protein large alpha 1,clathrin associated/assembly/adaptor protein,large,alpha 1,Plasma membrane adaptor HA 2/AP 2 adaptin alpha A subunit,Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit

Purification: Affinity purification

Immunogen: Synthetic peptide of human AP2A1

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000, IHC 1:25-100, ELISA 1:2000-5000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.6 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for alpha Adaptin

Target: alpha Adaptin (AP2A1) (Adaptor-Related Protein Complex 2, alpha 1 Subunit (AP2A1))

Alternative Name: AP2A1 (AP2A1 Products)

Synonyms: ADTAA antibody, AP2-ALPHA antibody, CLAPA1 antibody, adtaa antibody, clapa1 antibody, ap2-alpha antibody, AP2A1 antibody, Adtaa antibody, adaptor related protein complex 2 alpha 1 subunit antibody, adaptor-related protein complex 2, alpha 1 subunit antibody, AP-2 complex subunit alpha-1 antibody, AP2A1 antibody, ap2a1 antibody, Ap2a1 antibody, EDI_093420 antibody, EDI_259990 antibody

Background: This gene encodes the alpha 1 adaptin subunit of the adaptor protein 2 (AP-2) complex found in clathrin coated vesicles. The AP-2 complex is a heterotetramer consisting of two large adaptins (alpha or beta), a medium adaptin (mu), and a small adaptin (sigma). The complex is part of the protein coat on the cytoplasmic face of coated vesicles which links clathrin to receptors in vesicles. Alternative splicing of this gene results in two transcript variants encoding two different isoforms.

Molecular Weight: 108 kDa

NCBI Accession: NP_055018

UniProt: O95782

Pathways: Notch Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, EGFR Downregulation