GSK3 alpha antibody (Glycogen Synthase Kinase 3 alpha)

Details for Product anti-GSK3a Antibody No. ABIN5966250
Target
Reactivity
Human, Mouse, Rat
144
94
77
6
5
5
4
3
2
Host
Rabbit
131
33
2
Clonality
Polyclonal
Conjugate
This GSK3 alpha antibody is un-conjugated
13
11
8
5
5
5
5
3
3
3
3
3
3
1
1
1
1
1
1
1
Application
Western Blotting (WB)
130
78
72
22
16
15
13
9
5
4
2
2
1
Options
Immunogen Recombinant protein of human GSK3A
Isotype IgG
Purification Affinity purification
Target
Alternative Name GSK3 alpha (GSK3a Antibody Abstract)
Background

Synonyms: DKFZp686D0638,Glycogen synthase kinase 3 alpha,Glycogen synthase kinase-3 alpha,GSK 3 alpha,GSK 3A,GSK-3 alpha,Gsk3a,GSK3A,GSK3alpha,Serine/threonine protein kinase GSK3A

Background: This gene encodes a multifunctional Ser/Thr protein kinase that is implicated in the control of several regulatory proteins including glycogen synthase, and transcription factors, such as JUN. It also plays a role in the WNT and PI3K signaling pathways, as well as regulates the production of beta-amyloid peptides associated with Alzheimer's disease.

Molecular Weight

Observed_MW: 51kDa

Calculated_MW: 50kDa

Gene ID 2931
UniProt P49840
Pathways PI3K-Akt Signaling, WNT Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, cAMP Metabolic Process, Cellular Glucan Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process
Application Notes WB 1:500 - 1:1000
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Images
Image no. 1 for anti-Glycogen Synthase Kinase 3 alpha (GSK3a) antibody (ABIN5966250) Western blot analysis of extracts of various cell lines, using GSK3A antibody.