Integrin beta 2 antibody
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- Target See all Integrin beta 2 (ITGB2) Antibodies
- Integrin beta 2 (ITGB2)
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Integrin beta 2 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of human ITGB2
- Isotype
- IgG
- Top Product
- Discover our top product ITGB2 Primary Antibody
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- Application Notes
- WB 1:500-1:2000, IHC 1:25-1:100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.3 mg/mL
- Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- Integrin beta 2 (ITGB2)
- Alternative Name
- ITGB2 (ITGB2 Products)
- Synonyms
- CD18 antibody, LAD antibody, LCAMB antibody, LFA-1 antibody, MAC-1 antibody, MF17 antibody, MFI7 antibody, 2E6 antibody, AI528527 antibody, Cd18 antibody, Lfa1 antibody, ITGB2 antibody, itgb2 antibody, itgb2-a antibody, itgb2-b antibody, integrin subunit beta 2 antibody, integrin beta 2 antibody, integrin subunit beta 2 S homeolog antibody, ITGB2 antibody, Itgb2 antibody, itgb2.S antibody
- Background
- The product of this gene belongs to the integrin beta chain family of proteins. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. This gene encodes the integrin beta chain beta 2. A given chain may combine witHuman, Mouseultiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene.
- Molecular Weight
- 85 kDa
- UniProt
- P05107
- Pathways
- NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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