anti-Human PIAS2 antibody for Immunohistochemistry

Recommended PIAS2 Antibody (supplied by: Log in to see )

Antigen
Protein Inhibitor of Activated STAT, 2 (PIAS2) Antibodies
  • MGC83751
  • piasx
  • wu:fi05f09
  • PIAS2
  • 6330408K17Rik
  • AI462206
  • ARIP3
  • AU018068
  • Dib
  • Miz1
  • PIASxalpha
  • PIASxb
  • PIASxbeta
  • SIZ2
  • DIP
  • MIZ
  • MIZ1
  • PIASX
  • PIASX-ALPHA
  • PIASX-BETA
  • ZMIZ4
  • protein inhibitor of activated STAT 2 L homeolog
  • protein inhibitor of activated STAT 2
  • protein inhibitor of activated STAT, 2
  • pias2.L
  • PIAS2
  • pias2
  • Pias2
Epitope
C-Term
19
19
19
9
9
4
3
2
2
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Horse (Equine), Human, Mouse (Murine), Rabbit
135
57
46
21
14
11
11
7
5
4
2
2
1
Host
Rabbit
92
37
7
2
Clonality
Polyclonal
Conjugate
This PIAS2 antibody is un-conjugated
5
5
5
4
4
4
Application
Immunohistochemistry (IHC), Western Blotting (WB)
111
84
55
14
12
4
2
2
1
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

Submit your validation data for this product and get a full refund. I want to validate this product

Learn more

Available images

Catalog No. ABIN2779873
$ 289.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
9.289492 ABIN2466111 IHC ELISA WB Goat Internal Region Log in to see Polyclonal 0
9.289492 ABIN1031511 IHC ELISA WB Rabbit N-Term Log in to see Polyclonal 0
9.289492 ABIN2434174 IHC ELISA Rabbit IgG Log in to see Polyclonal 0
1 ABIN190909 IHC ELISA WB Goat Internal Region Log in to see Polyclonal 1
1 ABIN461934 ELISA IHC IHC (p) Goat AA 431-445 Log in to see Polyclonal 0
1 ABIN252941 IHC (p) IHC ELISA Goat Log in to see Polyclonal 1
1 ABIN1876855 IF IHC WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN2861224 IF IHC ELISA WB Rabbit N-Term Log in to see Polyclonal 0
1 ABIN2886141 ELISA IHC IHC (p) WB Rabbit IgG AA 10-59 Log in to see Polyclonal 0
1 ABIN4345423 IHC IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal 0
1 ABIN2335386 IHC ELISA Alkaline Phosphatase (AP) Goat IgG Log in to see Polyclonal 0
1 ABIN2335392 IHC ELISA Biotin Goat IgG Log in to see Polyclonal 0
1 ABIN2335395 IHC ELISA PE Goat IgG Log in to see Polyclonal 0
1 ABIN2335393 IHC ELISA FITC Goat IgG Log in to see Polyclonal 0
1 ABIN2335387 IHC ELISA APC Goat IgG Log in to see Polyclonal 0
1 ABIN2335385 IHC ELISA Goat IgG Log in to see Polyclonal 0
1 ABIN1923688 IHC ELISA WB Alkaline Phosphatase (AP) Rabbit IgG AA 518-547 Log in to see Polyclonal 0
1 ABIN1923689 IHC ELISA WB APC Rabbit IgG AA 518-547 Log in to see Polyclonal 0
1 ABIN1923690 IHC ELISA WB Biotin Rabbit IgG AA 518-547 Log in to see Polyclonal 0
1 ABIN1923691 IHC ELISA WB FITC Rabbit IgG AA 518-547 Log in to see Polyclonal 0

General

Antigen Protein Inhibitor of Activated STAT, 2 (PIAS2) Antibodies
Epitope C-Term
(19), (19), (19), (9), (9), (4), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Cow (Bovine), Dog (Canine), Horse (Equine), Human, Mouse (Murine), Rabbit
(135), (57), (46), (21), (14), (11), (11), (7), (5), (4), (2), (2), (1)
Host Rabbit
(92), (37), (7), (2)
Clonality
Polyclonal
Conjugate This PIAS2 antibody is un-conjugated
(5), (5), (5), (4), (4), (4)
Application Immunohistochemistry (IHC), Western Blotting (WB)
(111), (84), (55), (14), (12), (4), (2), (2), (1), (1)
Supplier Log in to see

Product Details anti-PIAS2 Antibody

Target Details PIAS2 Application Details Handling Images
Blocking Peptide Blocking peptide for this product available: ABIN981729
Sequence LSLIPVDPQY CPPMFLDSLT SPLTASSTSV TTTSPHESST HVSSSSSRSE
Predicted Reactivity Cow: 93%, Dog: 100%, Horse: 100%, Human: 93%, Mouse: 100%, Rabbit: 93%
Characteristics This is a rabbit polyclonal antibody against Pias2. It was validated on Western Blot and immunohistochemistry.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of mouse Pias2
Plasmids, Primers & others

Target Details PIAS2

Product Details anti-PIAS2 Antibody Application Details Handling Images back to top
Antigen
Alternative Name Pias2 (PIAS2 Antibody Abstract)
Background Pias2 functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. It plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway, the p53 pathway and the steroid hormone signaling pathway. It seems to be mostly involved in gene silencing. It binds to sumoylated ELK1 and enhances its transcriptional activity by preventing recruitment of HDAC2 by ELK1, thus reversing SUMO-mediated repression of ELK1 transactivation activity.
Alias Symbols: 6330408K17Rik, AI462206, ARIP3, AU018068, Dib, Miz1, PIASxalpha, PIASxb, PIASxbeta, SIZ2
Protein Interaction Partner: Pparg, Egr2, Plagl2, Trim32, Trp53, DHX9, Nfkb1, Gtf2i, GTF2IRD1, HDAC3,
Protein Size: 490
Molecular Weight 54 kDa
Gene ID 17344
NCBI Accession NM_001164167
UniProt Q8C5D8
Pathways JAK-STAT Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling

Application Details

Product Details anti-PIAS2 Antibody Target Details PIAS2 Handling Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 490 AA

Restrictions For Research Use only

Handling

Product Details anti-PIAS2 Antibody Target Details PIAS2 Application Details Images back to top
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Images

Product Details anti-PIAS2 Antibody Target Details PIAS2 Application Details Handling back to top
Supplier Images
Western Blotting (WB) image for anti-Protein Inhibitor of Activated STAT, 2 (PIAS2) (C-Term) antibody (ABIN2779873) WB Suggested Anti-Pias2 Antibody Titration: 0.2-1 ug/ml Positive Control: NIH/3T3 ...
Immunohistochemistry (IHC) image for anti-Protein Inhibitor of Activated STAT, 2 (PIAS2) (C-Term) antibody (ABIN2779873) Mouse Pancreas
Immunohistochemistry (IHC) image for anti-Protein Inhibitor of Activated STAT, 2 (PIAS2) (C-Term) antibody (ABIN2779873) Mouse Pancreas
Western Blotting (WB) image for anti-Protein Inhibitor of Activated STAT, 2 (PIAS2) (C-Term) antibody (ABIN2779873) WB Suggested Anti-Pias2 antibody Titration: 1 ug/mL Sample Type: Human heart