anti-Rabbit PIAS2 antibody for Western Blotting

Recommended PIAS2 Antibody (supplied by: Log in to see )

Antigen
Protein Inhibitor of Activated STAT, 2 (PIAS2) Antibodies
  • MGC83751
  • piasx
  • wu:fi05f09
  • PIAS2
  • 6330408K17Rik
  • AI462206
  • ARIP3
  • AU018068
  • Dib
  • Miz1
  • PIASxalpha
  • PIASxb
  • PIASxbeta
  • SIZ2
  • DIP
  • MIZ
  • MIZ1
  • PIASX
  • PIASX-ALPHA
  • PIASX-BETA
  • ZMIZ4
  • protein inhibitor of activated STAT 2 L homeolog
  • protein inhibitor of activated STAT 2
  • protein inhibitor of activated STAT, 2
  • pias2.L
  • PIAS2
  • pias2
  • Pias2
Epitope
N-Term
29
18
18
5
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus)
123
52
44
21
14
11
11
5
4
4
2
1
1
Host
Rabbit
82
35
7
2
Clonality
Polyclonal
Conjugate
This PIAS2 antibody is un-conjugated
4
4
4
4
4
4
Application
Western Blotting (WB)
101
72
49
14
13
4
3
2
1
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

Submit your validation data for this product and get a full refund. I want to validate this product

Learn more

Available images

Catalog No. ABIN2780293
$ 289.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
3.2908103 ABIN2779873 IHC WB Rabbit C-Term Log in to see Polyclonal 0
3.2908103 ABIN2785610 WB Rabbit N-Term Log in to see Polyclonal 1
3.2908103 ABIN2776423 WB Rabbit C-Term Log in to see Polyclonal 1
3.2908103 ABIN2785609 WB Rabbit N-Term Log in to see Polyclonal 0
3.2908103 ABIN2776422 WB Rabbit C-Term Log in to see Polyclonal 1
1 ABIN490650 ELISA WB Goat AA 185-196 Log in to see Polyclonal 0
1 ABIN202826 WB Rabbit IgG C-Term Log in to see Polyclonal 0
1 ABIN202828 WB Rabbit IgG C-Term Log in to see Polyclonal 0
1 ABIN799244 WB Rabbit AA 51-100 Log in to see Polyclonal 0
1 ABIN574875 WB Rabbit AA 81-130 Log in to see Polyclonal 0

General

Antigen Protein Inhibitor of Activated STAT, 2 (PIAS2) Antibodies
Epitope N-Term
(29), (18), (18), (5), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus)
(123), (52), (44), (21), (14), (11), (11), (5), (4), (4), (2), (1), (1)
Host Rabbit
(82), (35), (7), (2)
Clonality
Polyclonal
Conjugate This PIAS2 antibody is un-conjugated
(4), (4), (4), (4), (4), (4)
Application Western Blotting (WB)
(101), (72), (49), (14), (13), (4), (3), (2), (1), (1)
Supplier Log in to see

Product Details anti-PIAS2 Antibody

Target Details PIAS2 Application Details Handling Images
Blocking Peptide Blocking peptide for this product available: ABIN981730
Sequence SVFSLDGSSS PVEPDLPVAG IHSLPSTSIT PHSPSSPVGS VLLQDTKPTF
Predicted Reactivity Cow: 86%, Dog: 86%, Guinea Pig: 86%, Horse: 93%, Human: 93%, Mouse: 100%, Pig: 93%, Rabbit: 79%, Rat: 93%
Characteristics This is a rabbit polyclonal antibody against Pias2. It was validated on Western Blot.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide corresponding to a region of Mouse

Target Details PIAS2

Product Details anti-PIAS2 Antibody Application Details Handling Images back to top
Antigen
Alternative Name Pias2 (PIAS2 Antibody Abstract)
Background Pias2 functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor.Pias2 plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway, the p53 pathway and the steroid hormone signaling pathway. The effects of this transcriptional coregulation, transactivation or silencing may vary depending upon the biological context and PIAS2 isoform studied. However, it seems to be mostly involved in gene silencing.Pias2 binds to sumoylated ELK1 and enhances its transcriptional activity by preventing recruitment of HDAC2 by ELK1, thus reversing SUMO-mediated repression of ELK1 transactivation activity. Isoform PIASx-beta, but not isoform PIASx-alpha, promotes MDM2 sumoylation. Isoform PIASx-alpha promotes PARK7 sumoylation. Isoform PIASx-beta promotes NCOA2 sumoylation more efficiently than isoform PIASx-alpha
Alias Symbols: 6330408K17Rik, AI462206, ARIP3, AU018068, Dib, Miz1, PIASxalpha, PIASxb, PIASxbeta, SIZ2
Protein Interaction Partner: Pparg, Egr2, Plagl2, Trim32, Trp53, DHX9, Nfkb1, Gtf2i, GTF2IRD1, HDAC3,
Protein Size: 621
Molecular Weight 68 kDa
Gene ID 17344
NCBI Accession NM_008602, NP_032628
UniProt Q8C5D8
Pathways JAK-STAT Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling

Application Details

Product Details anti-PIAS2 Antibody Target Details PIAS2 Handling Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 621 AA

Restrictions For Research Use only

Handling

Product Details anti-PIAS2 Antibody Target Details PIAS2 Application Details Images back to top
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Images

Product Details anti-PIAS2 Antibody Target Details PIAS2 Application Details Handling back to top
Supplier Images
Western Blotting (WB) image for anti-Protein Inhibitor of Activated STAT, 2 (PIAS2) (N-Term) antibody (ABIN2780293) anti-Protein Inhibitor of Activated STAT, 2 (PIAS2) (N-Term) antibody