anti-Mouse (Murine) MAP2K7 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended MAP2K7 Antibody (supplied by: Log in to see )

Antigen
Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7) Antibodies
  • MAP2K7
  • 2
  • JNKK
  • Jnkk2
  • Mapkk7
  • Mek7
  • Mkk7
  • MAPKK7
  • MKK7
  • PRKMK7
  • SAPKK-4
  • SAPKK4
  • 5930412N11Rik
  • JNKK 2
  • MAPKK 7
  • MEK 7
  • Prkmk7
  • sek2
  • si:ch211-254d18.2
  • map2k7-A
  • mitogen-activated protein kinase kinase 7
  • mitogen activated protein kinase kinase 7
  • mitogen-activated protein kinase kinase 7 L homeolog
  • MAP2K7
  • Map2k7
  • map2k7
  • map2k7.L
Epitope
AA 2-40, N-Term
37
35
12
10
9
7
7
6
5
5
4
4
4
4
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
163
104
83
4
4
4
4
4
3
3
3
2
2
1
Host
Rabbit
145
24
Clonality
Polyclonal
Conjugate
This MAP2K7 antibody is un-conjugated
6
6
4
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
148
80
55
22
21
13
12
11
7
5
2
1
1
1
Options
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Catalog No. ABIN3043875
$ 280.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
11.472993 ABIN5950426 FACS ICC IF IHC IHC (p) IP WB Rabbit IgG AA 400-500 Log in to see SD20-87 0
10 ABIN5534517 IHC (p) WB Rabbit Ig Fraction AA 206-233 Log in to see Polyclonal 0
8.497463 ABIN743918 IF (p) IHC (p) WB Rabbit IgG pSer271, pThr275 Log in to see Polyclonal 0
4 ABIN658076 IHC (p) WB Rabbit Ig Fraction AA 206-233, Center Log in to see Polyclonal 0
4 ABIN5959700 ELISA IHC (p) WB Rabbit IgG pSer271 Log in to see Polyclonal 0
1 ABIN743927 IHC (p) WB HRP Rabbit IgG pSer271, pThr275 Log in to see Polyclonal 0
1 ABIN2884015 ELISA IHC IHC (p) WB Rabbit IgG pSer271 Log in to see Polyclonal 0
1 ABIN743920 IHC (p) WB Biotin Rabbit IgG pSer271, pThr275 Log in to see Polyclonal 0
1 ABIN4219086 IHC IHC (p) WB Rabbit pSer271 Log in to see Polyclonal 0
1 ABIN5541347 IHC (p) WB Rabbit pSer271 Log in to see Polyclonal 0
1 ABIN5541348 IHC (p) WB Rabbit pSer271 Log in to see Polyclonal 0
1 ABIN4951736 IHC (p) WB Rabbit IgG Log in to see Polyclonal 0

General

Antigen Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7) Antibodies
Epitope AA 2-40, N-Term
(37), (35), (12), (10), (9), (7), (7), (6), (5), (5), (4), (4), (4), (4), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(163), (104), (83), (4), (4), (4), (4), (4), (3), (3), (3), (2), (2), (1)
Host Rabbit
(145), (24)
Clonality
Polyclonal
Conjugate This MAP2K7 antibody is un-conjugated
(6), (6), (4), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(148), (80), (55), (22), (21), (13), (12), (11), (7), (5), (2), (1), (1), (1)
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Product Details anti-MAP2K7 Antibody

Target Details MAP2K7 Application Details Handling Images
Purpose Rabbit IgG polyclonal antibody for Dual specificity mitogen-activated protein kinase kinase 7(MAP2K7) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Sequence AASSLEQKLS RLEAKLKQEN REARRRIDLN LDISPQRPR
Cross-Reactivity (Details) No cross reactivity with other proteins.
Characteristics Rabbit IgG polyclonal antibody for Dual specificity mitogen-activated protein kinase kinase 7(MAP2K7) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: mitogen-activated protein kinase kinase 7
Protein Name: Dual specificity mitogen-activated protein kinase kinase 7
Purification Immunogen affinity purified.
Immunogen A synthetic peptide corresponding to a sequence at the N-terminus of human MEK7 (2-40aa AASSLEQKLSRLEAKLKQENREARRRIDLNLDISPQRPR), identical to the related mouse and rat sequences.
Isotype IgG
Plasmids, Primers & others

Target Details MAP2K7

Product Details anti-MAP2K7 Antibody Application Details Handling Images back to top
Antigen
Alternative Name MAP2K7 (MAP2K7 Antibody Abstract)
Background MAP2K7(Mitogen-activated protein kinase kinase 7), also known as MAP kinase kinase 7, MAPKK7, JNKK2, PRKMK7 or MKK7, is an enzyme that in humans is encoded by the MAP2K7 gene. This protein is a member of the mitogen-activated protein kinase kinase family. The MKK7 protein exists as six different isoforms with three possible N-termini (α, β, and γ isoforms) and two possible C-termini (1 and 2 isoforms). Schramek et al. (2011) showed that the doxorubicin-mediated DNA damage response in human A549 lung carcinoma cells caused rapid phosphorylation and upregulation of p53 (TP53). MKK7 knockdown reduced p53 phosphorylation, delayed p53 upregulation, and interfered with cell cycle arrest at G2/M. MKK7 was activated in primary lung tumors, and tumors with a p53 mutation showed even higher MKK7 phosphorylation. Schramek et al. (2011) concluded that MKK7 exerts its tumor suppressive function through p53.

Synonyms: c Jun N terminal kinase kinase 2 antibody|c-Jun N-terminal kinase kinase 2 antibody|Dual specificity mitogen activated protein kinase kinase 7 antibody|Dual specificity mitogen-activated protein kinase kinase 7 antibody|JNK activating kinase 2 antibody|JNK kinase 2 antibody|JNK-activating kinase 2 antibody|JNKK 2 antibody|Jnkk-2 antibody|Jnkk2 antibody| MAP kinase kinase 7 antibody|MAP2K 7 antibody|MAP2K7 antibody|MAPK/ERK kinase 7 antibody|MAPKK 7 antibody|MAPKK-7 antibody|MAPKK7 antibody|MEK 7 antibody|Mitogen activated protein kinase kinase 7 antibody|MKK 7 antibody|MKK-7 antibody|MKK7 antibody|MP2K7_HUMAN antibody|PRKMK 7 antibody|PRKMK-7 antibody| PRKMK7 antibody|Protein kinase mitogen activated kinase 7 antibody|Sek 2 antibody|Sek-2 antibody|Sek2 antibody|SKK4 antibody
Gene ID 5609
UniProt O14733
Pathways MAPK Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades

Application Details

Product Details anti-MAP2K7 Antibody Target Details MAP2K7 Handling Images back to top
Application Notes WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
Comment

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions For Research Use only

Handling

Product Details anti-MAP2K7 Antibody Target Details MAP2K7 Application Details Images back to top
Format Lyophilized
Reconstitution Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Concentration 500 μg/mL
Buffer Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Images

Product Details anti-MAP2K7 Antibody Target Details MAP2K7 Application Details Handling back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7) (AA 2-40), (N-Term) antibody (ABIN3043875) IHC(P): Human Intestinal Cancer Tissue
Immunohistochemistry (IHC) image for anti-Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7) (AA 2-40), (N-Term) antibody (ABIN3043875) IHC(P): Rat Lung Tissue
Western Blotting (WB) image for anti-Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7) (AA 2-40), (N-Term) antibody (ABIN3043875) anti-Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7) (AA 2-40), (N-Term) antibody (Image 3)
Immunohistochemistry (IHC) image for anti-Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7) (AA 2-40), (N-Term) antibody (ABIN3043875) IHC(P): Mouse Lung Tissue