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|Antigen||Dipeptidyl-Peptidase 4 (DPP4) Antibodies|
|Reactivity||Human, Rat (Rattus) Alternatives|
|Conjugate||This DPP4 antibody is un-conjugated Alternatives|
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
Product Details anti-DPP4 AntibodyTarget Details DPP4 Application Details Handling Images
|Specificity||Recognizes a glycoprotein of 110 kDa, identified as CD26 (Workshop VI, Code: N-L039). It is an atypical serine protease belonging to the prolyl oligopeptidase family. It is expressed on lymphocyte cells and is upregulated during T-cell activation. CD26 is also expressed on activated B cells and natural killer cells and abundantly on epithelia. CD26 is implicated in a variety of biological functions including T-cell activation, cell adhesion with extracellular matrix such as fibronectin or collagens, and in HIV infection. Cross-linking of CD26 using this antibody dramatically enhances the anti-CD3-induced IL-2 production. In Western blotting, this MAb reacts with only glycosylated CD26, but not with the deglycosylated form. It does not prevent ADA binding to CD26.|
|No Cross-Reactivity||Pig (Porcine), Sheep (Ovine)|
|Purification||Purified by Protein A/G|
|Immunogen||Human T cell clone|
|Plasmids, Primers & others|
Target Details DPP4Product Details anti-DPP4 Antibody Application Details Handling Images back to top
|Alternative Name||DPP4 (DPP4 Antibody Abstract)|
|Pathways||Peptide Hormone Metabolism, Regulation of Leukocyte Mediated Immunity|
Application DetailsProduct Details anti-DPP4 Antibody Target Details DPP4 Handling Images back to top
Positive Control: YT, HEP-G2 cells and lymphocytes. Lymph nodes and tonsils.
Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Immunohistochemistry (Frozen Only) (0.5-1.0 μg/mL for 30 minutes at RT) Optimal dilution for a specific application should be determined.
|Restrictions||For Research Use only|
HandlingProduct Details anti-DPP4 Antibody Target Details DPP4 Application Details Images back to top
|Buffer||10 mM PBS with 0.05 % BSA & 0.05 % azide.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Storage||4 °C,-80 °C|
|Storage Comment||Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.|
|Expiry Date||24 months|