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IL12 Protein

IL12 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE analysis. BCA Active
Catalog No. ABIN1112288
  • Target See all IL12 Proteins
    IL12 (Interleukin 12 (IL12))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Origin
    • 19
    • 10
    • 4
    • 1
    Human
    Source
    • 14
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Application
    Biochemical Assay (BCA)
    Sequence
    p35 Subunit: RNLPVATPDP GMFPCLHHSQ NLLRAVSNML QKARQTLEFY PCTSEEIDHE DITKDKTSTV EACLPLELTK NESCLNSRET SFITNGSCLA SRKTSFMMAL CLSSIYEDLK MYQVEFKTMN AKLLMDPKRQ IFLDQNMLAV IDELMQALNF NSETVPQKSS LEEPDFYKTK IKLCILLHAF RIRAVTIDRV MSYLNASp40 Subunit: IWELKKDVYV VELDWYPDAP GEMVVLTCDT PEEDGITWTL DQSSEVLGSG KTLTIQVKEF GDAGQYTCHK GGEVLSHSLL LLHKKEDGIW STDILKDQKE PKNKTFLRCE AKNYSGRFTC WWLTTISTDL TFSVKSSRGS SDPQGVTCGA ATLSAERVRG DNKEYEYSVE CQEDSACPAA EESLPIEVMV DAVHKLYENY TSSFFIRDII KPDPPKNLQL KPLKNSRQVE VSWEYPDTWS TPHSYFSLTF CVQVQGKSKR EKKDRVFTDK TSATVICRKN ASISVRAQDR YYSSSWSEWA SVPCS.
    No Cross-Reactivity
    Mouse (Murine), Monkey, Bacteria
    Characteristics
    The ED50 was determined by the induction of IFN-gamma from NK cells co-stimulated with IL-18 is less or equal to 1.0 ng/ml, corresponding to a specific activity of greater than or equal to 1 x 10^6 units/mg.
    Purity
    > 95 % as determined by SDS-PAGE analysis.
    Sterility
    0.2 μm filtered
    Endotoxin Level
    Endotoxin: 1.EU/µg determined by LAL method.
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  • Comment

    Length: 503 AA

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    We recommended spin the vial shortly prior to opening to bring the contents to the bottom. Lyophilized hIL12 should be reconstituted in deionized water to 0,1-1 µg/mL to regain full activity. These stock solutions should be apportioned into working aliquots and stored at -20 °C. Further dilutions should be made in low endotoxin medium or buffered solution with FBS or tissue culture grade BSA.
    Storage
    -20 °C
  • Target
    IL12 (Interleukin 12 (IL12))
    Alternative Name
    IL-12 (IL12 Products)
    Synonyms
    CLMF Protein, CLMF2 Protein, IL-12B Protein, NKSF Protein, NKSF2 Protein, p40 Protein, Il-12b Protein, Il12p40 Protein, Il-12p40 Protein, Il12 Protein, IL-12p40 Protein, IL-12 Protein, LOC100217488 Protein, IL-12p35 Protein, Il-12a Protein, Ll12a Protein, p35 Protein, IL12p40 Protein, IL12B Protein, IL-12 p35 Protein, interleukin 12B Protein, interleukin 12A Protein, interleukin 12b Protein, interleukin 12a Protein, Interleukin 12 level Protein, IL12B Protein, IL12A Protein, Il12b Protein, Il12a Protein, IL12 Protein, il12a Protein
    Molecular Weight
    75 kDa.
    Pathways
    JAK-STAT Signaling, TLR Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation, Cancer Immune Checkpoints, Inflammasome
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