IL12 Protein
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- Target See all IL12 Proteins
- IL12 (Interleukin 12 (IL12))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Mouse
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Source
- CHO Cells
- Sequence
- RVIPVSGPAR CLSQSRNLLK TTDDMVKTAR EKLKHYSCTA EDIDHEDITR DQTSTLKTCL PLELHKNESC LATRETSSTT RGSCLPPQKT SLMMTLCLGS IYEDLKMYQT EFQAINAALQ NHNHQQIILD KGMLVAIDEL MQSLNHNGET LRQKPPVGEA DPYRVKMKLC ILLHAFSTRV VTINRVMGYL SSA
- Characteristics
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Purified recombinant Mouse IL12 protein
Expression System: CHO cells
Bioactivity: The ED50 was determined by the stimulation of IFN-gamma production by Mouse splenocytes co-stimulated with IL-18 is 1 x 10^7 units/mg. - Purity
- > 98 % pure
- Sterility
- Sterile filtered
- Endotoxin Level
- < 0.1 ng per μg (1 EU/μg).
- Top Product
- Discover our top product IL12 Protein
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute in PBS to a concentration 0.1 - 1.0 mg/mL.
- Buffer
- Lyophilized from PBS, pH 7.2, sterile filtered.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- RT/-20 °C
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- Target
- IL12 (Interleukin 12 (IL12))
- Alternative Name
- IL12 (IL12 Products)
- Synonyms
- CLMF Protein, CLMF2 Protein, IL-12B Protein, NKSF Protein, NKSF2 Protein, p40 Protein, Il-12b Protein, Il12p40 Protein, Il-12p40 Protein, Il12 Protein, IL-12p40 Protein, IL-12 Protein, LOC100217488 Protein, IL-12p35 Protein, Il-12a Protein, Ll12a Protein, p35 Protein, IL12p40 Protein, IL12B Protein, IL-12 p35 Protein, interleukin 12B Protein, interleukin 12A Protein, interleukin 12b Protein, interleukin 12a Protein, Interleukin 12 level Protein, IL12B Protein, IL12A Protein, Il12b Protein, Il12a Protein, IL12 Protein, il12a Protein
- Background
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IL12 is a potent regulator of cell mediated immune responses and it induces IFN-gamma production by NK and T cells. It is produced by activated monocytes/macrophage cells, B lymphocytes and connective tissue type mast cells. Among its biological activities IL12 promotes the growth and activity of activated NK, CD4+ and CD8+ cells and induces the development of IFN-gamma producing Th1 cells.
Alternative Names: TCMF protein, CTL maturation factor protein, IL12, TSF protein, IL-12 protein, Interleukin 12 protein, IL-12, IL 12 protein, IL-12 protein, CLMF protein, IL 12, NKSF protein, Cytotoxic lymphocyte maturation factor protein - Molecular Weight
- 75 kDa
- Pathways
- JAK-STAT Signaling, TLR Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation, Cancer Immune Checkpoints, Inflammasome
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