RGS17 antibody

Catalog No. ABIN5703670

Product Details anti-RGS17 Antibody

Target: RGS17 (Regulator of G-Protein Signaling 17 (RGS17))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS17 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)

Immunogen: regulator of G-protein signaling 17

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

mouse lung tissue were subjected to SDS PAGE followed by western blot with FNab07268(RGS17 antibody) at dilution of 1:1000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for RGS17

Target: RGS17 (Regulator of G-Protein Signaling 17 (RGS17))

Alternative Name: RGS17 (RGS17 Products)

Synonyms: RGS17 antibody, zgc:92802 antibody, MGC179306 antibody, RGS-17 antibody, RGSZ2 antibody, hRGS17 antibody, 6430507P11Rik antibody, Rgsz2 antibody, regulator of G protein signaling 17 antibody, regulator of G-protein signaling 17 antibody, RGS17 antibody, Rgs17 antibody, rgs17 antibody

Background: Synonyms:RGSZ2 Background:Regulates G protein-coupled receptor signaling cascades, including signaling via muscarinic acetylcholine receptor CHRM2 and dopamine receptor DRD2. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form(PubMed:15096504). Binds selectively to GNAZ and GNAI2 subunits, accelerates their GTPase activity and regulates their signaling activities. Negatively regulates mu-opioid receptor-mediated activation of the G-proteins(By similarity).

Gene ID: 26575

UniProt: Q9UGC6

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling