anti-Mouse (Murine) Caspase 4 antibody for Western Blotting

Recommended Caspase 4 Antibody (supplied by: Log in to see )

Antigen
Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) Antibodies
  • ICE(rel)II
  • ICEREL-II
  • ICH-2
  • Mih1/TX
  • TX
  • Casp11
  • CASP13
  • CASP1
  • CASP4
  • Caspl
  • ich-3
  • Casp4
  • caspase 4
  • caspase 4, apoptosis-related cysteine peptidase
  • caspase-4
  • CASP4
  • Casp4
  • LOC100731032
Reactivity
Mouse (Murine), Rat (Rattus)
207
103
42
22
3
1
1
Host
Rat
202
27
21
17
7
Clonality
Monoclonal
Conjugate
This Caspase 4 antibody is un-conjugated
18
15
4
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunoprecipitation (IP), ELISA, Western Blotting (WB)
263
97
95
56
31
25
19
17
17
9
3
2
2
1
Options
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Available images

Catalog No. ABIN2745522
$ 510.31
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
22.55837 ABIN2745523 FACS IP ELISA WB Rat IgG1 Log in to see 4-00E-11 0
12.755764 ABIN3183668 ELISA IHC WB Rabbit IgG Internal Region Log in to see Polyclonal 0
12.755764 ABIN2745521 ELISA WB Mouse IgG2b AA 81-373 Log in to see Flamy-2 0
12.755764 ABIN6137966 WB Rabbit Log in to see Polyclonal 0
10.802607 ABIN6260482 ELISA IHC WB Rabbit IgG Log in to see Polyclonal 0
10.802607 ABIN6260486 ELISA ICC IF IHC WB Rabbit IgG Log in to see Polyclonal 0
10.802607 ABIN1858236 ICC IHC WB Rabbit IgG AA 969-1165 Log in to see Polyclonal 0
10.802607 ABIN2902454 IF/ICC IHC IP WB Rabbit AA 969-1165 Log in to see Polyclonal 0
10 ABIN2688867 WB Rat IgG2a, kappa Log in to see 17D9 8
10 ABIN214595 IHC IHC (p) WB Rabbit Log in to see Polyclonal 0
9.302607 ABIN222879 WB Rabbit IgG Log in to see Polyclonal 1
9.302607 ABIN222883 WB Rabbit IgG Log in to see Polyclonal 1
9.302607 ABIN2477914 IHC (p) WB Rabbit IgG N-Term Log in to see Polyclonal 3
7.8026066 ABIN498677 IHC (p) WB Rabbit Log in to see Polyclonal 0
7.8026066 ABIN1858249 ICC IHC WB Rabbit IgG AA 81-266 Log in to see Polyclonal 0
7.8026066 ABIN1077914 ICC IHC WB Rabbit IgG AA 286-373 Log in to see Polyclonal 0
7.8026066 ABIN5693194 ELISA WB Rabbit AA 108-195 Log in to see Polyclonal 0
7.8026066 ABIN1031297 IHC ELISA WB Rabbit N-Term Log in to see Polyclonal 0
7.8026066 ABIN2899477 IF/ICC IHC IP WB Rabbit AA 286-373 Log in to see Polyclonal 0
7.8026066 ABIN2899478 IF/ICC IHC IP WB Rabbit AA 81-266 Log in to see Polyclonal 0

General

Antigen Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) Antibodies
Reactivity Mouse (Murine), Rat (Rattus)
(207), (103), (42), (22), (3), (1), (1)
Host Rat
(202), (27), (21), (17), (7)
Clonality (Clone)
Monoclonal   ( )
Conjugate This Caspase 4 antibody is un-conjugated
(18), (15), (4), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Flow Cytometry (FACS), Immunoprecipitation (IP), ELISA, Western Blotting (WB)
(263), (97), (95), (56), (31), (25), (19), (17), (17), (9), (3), (2), (2), (1)
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Product Details anti-Caspase 4 Antibody

Target Details Caspase 4 Application Details Handling Images
Specificity Recognizes mouse and rat full-length caspase-11 protein. Detects two bands of ~38 kDa and ~43 kDa by Western blot.
Cross-Reactivity Mouse (Murine), Rat (Rattus)
Purity >95 % (SDS-PAGE)
Endotoxin Level <0.1EU/μg purified protein (LAL test, Lonza).
Immunogen Recombinant mouse caspase-11 (p20 fragment).
Clone 8A5
Isotype IgG1
Plasmids, Primers & others

Target Details Caspase 4

Product Details anti-Caspase 4 Antibody Application Details Handling Images back to top
Antigen
Alternative Name Caspase-11 (CASP4 Antibody Abstract)
Background Caspase-11 not only activates caspase-1, that is required for the maturation of proinflammatory cytokines such as interleukin-1 (IL-1) and interleukin-18 (IL-18), but also activates caspase-3, leading to cellular apoptosis under pathological conditions. In most cells, caspase-11 is only expressed upon induction with pro-inflammatory stimuli. Caspase-11 is an essential mediator of endotoxic shock and caspase-11-deficient mice are resistant to endotoxic shock. LPS-induced caspase-11 regulates lymphocyte apoptosis by activating both caspase-3 and caspase-7.
UniProt P70343
Pathways Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity

Application Details

Product Details anti-Caspase 4 Antibody Target Details Caspase 4 Handling Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-Caspase 4 Antibody Target Details Caspase 4 Application Details Images back to top
Format Liquid
Concentration 1 mg/mL
Buffer In PBS containing 0.02 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C.
Expiry Date 12 months

Images

Product Details anti-Caspase 4 Antibody Target Details Caspase 4 Application Details Handling back to top
Supplier Images
Immunoprecipitation (IP) image for anti-Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) antibody (ABIN2745522) Immunoprecipitation of caspase-11 using anti-caspase-11 mAbs (4E11 and 8A5)
Flow Cytometry (FACS) image for anti-Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) antibody (ABIN2745522) Flow cytometry data of overexpressed FLAG-tagged caspase-11 in 293T cells using anti-...
Western Blotting (WB) image for anti-Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) antibody (ABIN2745522) Western blot using anti-Caspase-11 (mouse), mAb (8A5) detecting endogenous caspase-1...