anti-Human Integrin beta 2 antibody for Enzyme Immunoassay

Recommended Integrin beta 2 Antibody (supplied by: Log in to see )

Antigen
Integrin beta 2 (ITGB2) Antibodies
  • CD18
  • LAD
  • LCAMB
  • LFA-1
  • MAC-1
  • MF17
  • MFI7
  • 2E6
  • AI528527
  • Cd18
  • Lfa1
  • ITGB2
  • itgb2
  • itgb2-a
  • itgb2-b
  • integrin subunit beta 2
  • integrin beta 2
  • integrin subunit beta 2 S homeolog
  • ITGB2
  • Itgb2
  • itgb2.S
Reactivity
Human, Mouse (Murine)
522
202
121
35
23
21
9
4
4
3
3
3
3
3
2
1
1
Host
Mouse
366
179
144
9
3
1
Clonality
Monoclonal
Conjugate
This Integrin beta 2 antibody is un-conjugated
82
71
49
27
12
12
9
9
7
5
5
5
5
5
5
4
4
4
4
4
4
3
3
3
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF)
465
299
181
179
93
89
75
73
65
40
27
15
13
11
7
6
3
1
1
1
1
1
1
1
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Catalog No. ABIN1105953
$ 445.50
Plus shipping costs $45.00

General

Antigen Integrin beta 2 (ITGB2) Antibodies
Reactivity Human, Mouse (Murine)
(522), (202), (121), (35), (23), (21), (9), (4), (4), (3), (3), (3), (3), (3), (2), (1), (1)
Host Mouse
(366), (179), (144), (9), (3), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This Integrin beta 2 antibody is un-conjugated
(82), (71), (49), (27), (12), (12), (9), (9), (7), (5), (5), (5), (5), (5), (5), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunofluorescence (IF)
(465), (299), (181), (179), (93), (89), (75), (73), (65), (40), (27), (15), (13), (11), (7), (6), (3), (1), (1), (1), (1), (1), (1), (1)
Pubmed 3 references available
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Product Details anti-Integrin beta 2 Antibody

Target Details Integrin beta 2 Application Details Handling References for anti-Integrin beta 2 antibody (ABIN1105953) Images
Specificity Recognizes CD18 also known as ITGB2 (integrin beta chain beta 2).
Cross-Reactivity (Details) Species reactivity (tested):Human, Mouse.
Purification Ascites
Clone 1-00E-013
Isotype IgG2b
Plasmids, Primers & others

Target Details Integrin beta 2

Product Details anti-Integrin beta 2 Antibody Application Details Handling References for anti-Integrin beta 2 antibody (ABIN1105953) Images back to top
Antigen
Alternative Name CD18 / ITGB2 (ITGB2 Antibody Abstract)
Background CD18, also known as ITGB2 (integrin beta chain beta 2). Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. CD18 is expressed by most leucocytes. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene.Synonyms: 95 subunit beta, Cell surface adhesion glycoproteins LFA-1/CR3/p150, Complement receptor C3 subunit beta, Integrin beta-2, MFI7
Molecular Weight 85 kDa
Gene ID 3689
Pathways NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation

Application Details

Product Details anti-Integrin beta 2 Antibody Target Details Integrin beta 2 Handling References for anti-Integrin beta 2 antibody (ABIN1105953) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-Integrin beta 2 Antibody Target Details Integrin beta 2 Application Details References for anti-Integrin beta 2 antibody (ABIN1105953) Images back to top
Format Liquid

References for anti-Integrin beta 2 antibody (ABIN1105953)

Product Details anti-Integrin beta 2 Antibody Target Details Integrin beta 2 Application Details Handling Images back to top
Background publications

Chakrabarti, Patel: "The atypical zeta (zeta) isoform of protein kinase C regulates CD11b/CD18 activation in human neutrophils." in: Microcirculation (New York, N.Y. : 1994), Vol. 15, Issue 6, pp. 555-67, 2008

Doisne, Castaigne, Deruyffelaere, Dieu-Nosjean, Chamot, Alcaide-Loridan, Charron, Al-Daccak: "The context of HLA-DR/CD18 complex in the plasma membrane governs HLA-DR-derived signals in activated monocytes." in: Molecular immunology, Vol. 45, Issue 3, pp. 709-18, 2007

Li, Tang, Puan, Law, Tan: "The cytosolic protein talin induces an intermediate affinity integrin alphaLbeta2." in: The Journal of biological chemistry, Vol. 282, Issue 33, pp. 24310-9, 2007

Images

Product Details anti-Integrin beta 2 Antibody Target Details Integrin beta 2 Application Details Handling References for anti-Integrin beta 2 antibody (ABIN1105953) back to top
Supplier Images
Immunofluorescence (IF) image for anti-Integrin beta 2 (ITGB2) antibody (ABIN1105953) anti-Integrin beta 2 (ITGB2) antibody
Immunofluorescence (IF) image for anti-Integrin beta 2 (ITGB2) antibody (ABIN1105953) anti-Integrin beta 2 (ITGB2) antibody (Image 2)