anti-Human Integrin beta 2 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended Integrin beta 2 Antibody (supplied by: Log in to see )

Antigen
Integrin beta 2 (ITGB2) Antibodies
  • CD18
  • LAD
  • LCAMB
  • LFA-1
  • MAC-1
  • MF17
  • MFI7
  • 2E6
  • AI528527
  • Cd18
  • Lfa1
  • ITGB2
  • itgb2
  • itgb2-a
  • itgb2-b
  • integrin subunit beta 2
  • integrin beta 2
  • integrin subunit beta 2 S homeolog
  • ITGB2
  • Itgb2
  • itgb2.S
Epitope
N-Term
46
35
26
22
16
15
14
14
12
5
5
5
5
5
5
4
4
4
4
4
3
3
3
2
2
2
2
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
476
209
116
40
38
21
20
13
5
4
3
3
3
3
3
2
1
1
Host
Rabbit
365
159
158
11
3
1
Clonality
Polyclonal
Conjugate
This Integrin beta 2 antibody is un-conjugated
83
73
50
27
14
11
10
9
8
8
8
6
6
6
6
6
6
5
5
3
3
3
3
3
3
3
3
2
2
2
2
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
477
291
198
150
98
93
77
71
54
40
28
17
11
9
7
6
4
2
1
1
1
1
1
1
1
Supplier
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Catalog No. ABIN1105952
$ 379.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
12.839581 ABIN669411 IF (p) IHC (p) WB Rabbit IgG AA 724-769 Log in to see Polyclonal 1
12.839581 ABIN269011 CyTOF FACS IHC IHC (fro) IHC (p) IP WB Mouse IgG1 AA 534-546 Log in to see MEM-48 0
12.839581 ABIN298664 Func FACS IHC (fro) IHC (p) IP WB Mouse IgG1 Log in to see MEM-48 0
12.839581 ABIN743723 IF (p) IHC (p) WB Rabbit IgG pSer756, pThr758, pThr759, AA 724-769 Log in to see Polyclonal 0
12.839581 ABIN1714264 IF (p) IHC (p) Rabbit IgG AA 724-769, pThr758 Log in to see Polyclonal 0
12.839581 ABIN4327008 IHC IHC (p) WB Rabbit IgG Log in to see Polyclonal 0
12.839581 ABIN4327009 IHC IHC (p) WB Rabbit IgG Log in to see Polyclonal 0
12.839581 ABIN4911227 IHC (p) WB Mouse IgG1 Log in to see 534CT6-2-1 0
1 ABIN2749019 Func IHC (f) FACS IP IHC (p) WB Mouse IgG1 Log in to see MEM-48 12
1 ABIN192094 FACS Func IHC (f) IHC (p) IP WB PE Mouse IgG1 AA 534-546 Log in to see MEM-48 20
1 ABIN94007 FACS Func IHC (f) IHC (p) IP WB Biotin Mouse IgG1 AA 534-546 Log in to see MEM-48 20
1 ABIN94008 FACS Func IHC (f) IHC (p) IP WB FITC Mouse IgG1 AA 534-546 Log in to see MEM-48 20
1 ABIN125688 FACS Func IHC (f) IHC (p) IP WB APC Mouse IgG1 AA 534-546 Log in to see MEM-48 19
1 ABIN94005 FACS Func IHC (f) IHC (p) IP WB Mouse IgG1 AA 534-546 Log in to see MEM-48 19
1 ABIN3043260 ICC IHC (p) WB Rabbit IgG AA 404-769 Log in to see Polyclonal 0
1 ABIN462406 Func FACS IHC (fro) IHC (p) IP WB Mouse IgG1 AA 534-546 Log in to see MEM-48 0
1 ABIN3044225 IHC (p) WB Rabbit IgG AA 732-748, C-Term Log in to see Polyclonal 0
1 ABIN3043698 IHC (p) WB Rabbit IgG AA 24-58, N-Term Log in to see Polyclonal 0
1 ABIN1714270 IF (p) IHC (p) WB Rabbit IgG AA 724-769, pSer756 Log in to see Polyclonal 0
1 ABIN1495137 IHC (p) WB Rabbit N-Term Log in to see Polyclonal 0

General

Antigen Integrin beta 2 (ITGB2) Antibodies
Epitope N-Term
(46), (35), (26), (22), (16), (15), (14), (14), (12), (5), (5), (5), (5), (5), (5), (4), (4), (4), (4), (4), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(476), (209), (116), (40), (38), (21), (20), (13), (5), (4), (3), (3), (3), (3), (3), (2), (1), (1)
Host Rabbit
(365), (159), (158), (11), (3), (1)
Clonality
Polyclonal
Conjugate This Integrin beta 2 antibody is un-conjugated
(83), (73), (50), (27), (14), (11), (10), (9), (8), (8), (8), (6), (6), (6), (6), (6), (6), (5), (5), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(477), (291), (198), (150), (98), (93), (77), (71), (54), (40), (28), (17), (11), (9), (7), (6), (4), (2), (1), (1), (1), (1), (1), (1), (1)
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Product Details anti-Integrin beta 2 Antibody

Target Details Integrin beta 2 Application Details Handling Images
Specificity This antibody detects CD18 / ITGB2 (N-term). No cross reactivity with other proteins.
Cross-Reactivity (Details) Species reactivity (tested):Human, rat, mouse
Purification Immunogen affinity purified
Immunogen A synthetic peptide mapping at the N-terminal of human Integrin beta2 .Remarks: Sequence differs from the related mouse sequence by five amino acids.
Isotype IgG

Target Details Integrin beta 2

Product Details anti-Integrin beta 2 Antibody Application Details Handling Images back to top
Antigen
Alternative Name CD18 / ITGB2 (ITGB2 Antibody Abstract)
Background The beta-2 integrin chain gene is designated ITGB2 and the leukocyte antigen has been designated CD18. The 3 alpha integrin chains associated individually with the beta-2 chain as a heterodimer have gene designations of ITGAL, ITGAM, and ITGAX, and leukocyte antigen designations of CD11A, CD11B, and CD11C, respectively. The expression of CD18 was increased in lymphoblastoid cells from persons with Down syndrome, consistent with the location of the gene on chromosome 211. The ITGB2 gene spans approximately 40 kb and contains 16 exons and all exon/intron boundaries conform to the GT/AG splicing consensus. Furthermore,ITGB2 was constitutively clustered. Although it was expressed on the cell surface at normal levels and was capable of function following extracellular stimulation, it could not be activated via the Synonyms: 95 subunit beta, Cell surface adhesion glycoproteins LFA-1/CR3/p150, Complement receptor C3 subunit beta, Integrin beta-2, MFI7
Gene ID 3689
NCBI Accession NP_000202
UniProt P05107
Pathways NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation

Application Details

Product Details anti-Integrin beta 2 Antibody Target Details Integrin beta 2 Handling Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-Integrin beta 2 Antibody Target Details Integrin beta 2 Application Details Images back to top
Reconstitution 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Buffer 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3
Preservative Sodium azide, Thimerosal (Merthiolate)
Precaution of Use This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Images

Product Details anti-Integrin beta 2 Antibody Target Details Integrin beta 2 Application Details Handling back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Integrin beta 2 (ITGB2) (N-Term) antibody (ABIN1105952) IHC staining with Integrin β2 Polyclonal Antibody