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Hot research topic: The Solute Carrier Proteins (SLC)

Pharmaceutical companies are getting increasingly interested in the solute carrier (SLC) protein family. Several are active in the blood brain barrier and are being investigated as potential aids for drugs delivery by allowing new drugs to mimic the specific solutes.
Examples are SLC7A6 involved in amino acid transport, SLC2A1 involved in hexose (glucose) transport, SLCO1B1 involved in transport of organic anions and opioids, SLC6A8 involved in transport of brain creatine, etc. Protein SLC6A4 for instance is a strong candidate as a drug target, because it is a serotonin transporter that removes the neurotransmitter from the synaptic cleft and thus terminating its function.

The solute carrier (SLC) proteins constitute a group of membrane-integrated transporters. Solutes that are transported by the various SLC group members are extraordinarily diverse and include both charged and uncharged organic molecules as well as inorganic ions. Below are several examples of SLCs that are being offered on antibodies-online.com

Antibodies against Solute Carrier Proteins (SLC)
Order Number Antigen Applications
ABIN185672 GLUT8 / SLC2A8 ELISA
ABIN238576 KCC1 / SLC12A4 ELISA, Western Blotting (WB)
ABIN238578 KCC3 / SLC12A6 ELISA, Western Blotting (WB)
ABIN238577 KCC4 / SLC12A7 ELISA
ABIN185496 SLC9A3R2 (isoform A3) ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
ABIN335162 Slc10a2 (mouse) ELISA, Western Blotting (WB)
ABIN184612 SLC16A7 / MCT2 ELISA, Western Blotting (WB)
ABIN334492 SLC22A16 ELISA
ABIN335163 SLC22A17 ELISA
ABIN185638 SLC24A5 ELISA, Western Blotting (WB)
ABIN335164 SLC26A5 / prestin ELISA
ABIN185394 SLC6A4 / 5HTT / SERT ELISA, Western Blotting (WB)
ABIN190899 SLC7A11 ELISA, Western Blotting (WB)
ABIN185512 UCP1 ELISA, Western Blotting (WB)
ABIN190824 Uncoupling protein 2 / UCP2 ELISA, Western Blotting (WB)
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