SARS-CoV-2 Spike Protein (B.1.617.2 - delta) (rho-1D4 tag)
-
- Key Features
-
- Recombinant trimeric S protein of the SARS-CoV-2 variant of concern B.1.617.
- Contains T19R, L452R, T478K, D614G, P681R and D950N mutations characteristic for the SARS-CoV-2 delta variant (B.1.617.2).
- Target See all SARS-CoV-2 Spike Proteins
- SARS-CoV-2 Spike
- Protein Type
- Recombinant
- Protein Characteristics
- B.1.617.2 - delta
-
Origin
- SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Delta
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This SARS-CoV-2 Spike protein is labelled with rho-1D4 tag.
- Application
- ELISA, Ligand Binding Assay (LBA)
- Purpose
- This is the spike protein of the mutant strain B.1.617, also commonly known as the "Delta mutant".
- Sequence
- Full-length sequence (aa 1 – 1273), 1284 amino acids (including Rho1D4 tag and linker)
- Specificity
- Mutation that differ from "original" SPIKE protein: T19R, Del 157-158, L452R, T478K, D614G, P681R, D950N
- Characteristics
- All viruses undergo fast mutations and adept quickly to the countermeasures that the immune systems creates against them. SARS-CoV-2 of the COVID-19 pandemic is no exception here. During the pandemic multiple mutant strains arose.
- Purification
- Affnity Chromatography
- Purity
- > 98% as derermined by SDS-PAGE
- Top Product
- Discover our top product SARS-CoV-2 Spike Protein
-
-
- Comment
-
Further modifications:
- furin cleavage site "682-RRAR|SV-687" mutated to "682-GSAG|PP-687"
- C-terminal Rho1D4 tag fused with spacer "GSSG" to protein sequence - Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- 20 mM Hepes pH 7.5; 150 mM NaCl, 0.001 % LMNG
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Avoid freeze-thaw cycles
-
- Target
- SARS-CoV-2 Spike
- Alternative Name
- SARS2 Spike glycoprotein (SARS-CoV-2 Spike Products)
- Synonyms
- E2 Protein, E2 glycoprotein precursor Protein, Surface Glycoprotein Protein, S Protein
- Target Type
- Viral Protein
- Molecular Weight
- 141903 Da
- UniProt
- P0DTC2
-