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SARS-CoV-2 Spike Protein (Trimer, XBB.1.5 - Omicron) (Biotin,His-Avi Tag)

Origin: SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Omicron Host: HEK-293 Cells Recombinant
Catalog No. ABIN7448120
  • Target See all SARS-CoV-2 Spike Proteins
    SARS-CoV-2 Spike
    Protein Type
    Recombinant
    Protein Characteristics
    Trimer, XBB.1.5 - Omicron
    Origin
    • 190
    • 36
    • 9
    • 8
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Omicron
    Source
    • 174
    • 7
    • 2
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This SARS-CoV-2 Spike protein is labelled with Biotin,His-Avi Tag.
    Purpose
    Biotinylated SARS-CoV-2 Spike Trimer Protein, His,Avitag™ (XBB.1.5/Omicron)
    Characteristics
    Biotinylated SARS-CoV-2 Spike Trimer Protein, His,Avitag (XBB.1.5/Omicron) is expressed from human 293 cells (HEK293). It contains AA Val 16 - Pro 1213 (Accession # QHD43416.1 (T19I, LPP24-26del, A27S, V83A, G142D, Y144del, H146Q, Q183E, V213E, G252V, G339H, R346T, L368I, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, V445P, G446S, N460K, S477N, T478K, E484A, F486P, F490S, Q498R, N501Y, Y505H, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H, N969K, R683A, R685A, F817P, A892P, A899P, A942P, K986P, V987P). The spike mutations are identified on the SARS-CoV-2 Omicron variant (Pango lineage: XBB.1.5). The recombinant protein is expressed from human 293 cells (HEK293) with T4 fibritin trimerization motif and a polyhistidine tag at the C-terminus. Proline substitutions (F817P, A892P, A899P, A942P, K986P, V987P) and alanine substitutions (R683A and R685A) are introduced to stabilize the trimeric prefusion state of SARS-CoV-2 S protein and abolish the furin cleavage site, respectively. Predicted N-terminus: Val 16
    Endotoxin Level
    1.0 EU per μg
    Top Product
    Discover our top product SARS-CoV-2 Spike Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Storage
    -20 °C
    Storage Comment
    For long term storage, the product should be stored at lyophilized state at -20°C or lower. Please avoid repeated freeze-thaw cycles.
    This product is stable after storage at:
    -20°C to -70°C for 12 months in lyophilized state
    -70°C for 3 months under sterile conditions after reconstitution.
  • Target
    SARS-CoV-2 Spike
    Abstract
    SARS-CoV-2 Spike Products
    Synonyms
    E2 Protein, E2 glycoprotein precursor Protein, Surface Glycoprotein Protein, S Protein
    Molecular Weight
    139.7 kDa
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