Recent study uses cystathionase antibody from

Cancer cells have a high demand for cysteine as precursor of the antioxidant, glutathione, that is required to promote cell growth and division. The aim of a recent study by S Kandil, L Brennan, and GJ McBean, was to evaluate the relative contribution of different metabolic pathways to glutathione synthesis in astrocytoma/glioblastoma cells. The major finding was, that glutathione depletion causes a - and -mediated increase in expression of that promotes flux through the transsulfuration pathway to compensate for loss of glutathione in C6 glioma cells. This study has been carried out with cystathionase antibodies supplied by